Integrin beta 3/CD61 [p Tyr785] Antibody - BSA Free

Western Blot: Integrin beta 3/CD61 [p Tyr785] Antibody [NB100-81995] - Analysis of extracts from HUVEC cells using Integrin b3(Phospho-Tyr785) Antibody and the same antibody preincubated with blocking peptide.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Integrin beta 3/CD61 [p Tyr785] Antibody - BSA Free Summary

• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Integrin beta 3/CD61 around the phosphorylation site of tyrosine 785 (I-T-YP-R-G).
• Modification: p Tyr785
• Specificity: Detects endogenous levels of Integrin beta 3/CD61 only when phosphorylated at tyrosine 785.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ITGB3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000
• Theoretical MW: 87 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  Integrin beta 3/CD61 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Integrin beta 3/CD61 [p Tyr785] Antibody - BSA Free

• CD61 antigen
• CD61
• GP3A
• GP3Aplatelet glycoprotein IIIa
• GPIIIA
• GPIIIaintegrin beta-3
• INGRB3
• Integrin beta 3
• integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
• ITG B3
• ITGB3
• Platelet membrane glycoprotein IIIa

Background

Human Integrin beta 3 (CD61) antigen is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. The integrin beta 3 chain of the vitronectin receptor and GPIIb/IIIa complex. The beta 3 integrin chain is a 90-110 kDa glycoprotein polypeptide which is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGB3
• Entrez:
  • 3690(Human)
  • 16416(Mouse)
  • 29302(Rat)
• Uniprot:
  • P05106()