Integrin beta 3/CD61 Products

Antibodies
Integrin beta 3/CD61 Antibody ...
Integrin beta 3/CD61 Antibody (BV4)
NB600-1342
Species: Hu, Mu, Rt, Bv
Applications: WB, Func, IA, IHC, IHC-Fr, IHC-P, IP
Host: Mouse Monoclonal
Integrin beta 3/CD61 Antibody ...
Integrin beta 3/CD61 Antibody (PM6...
NBP1-28398
Species: Hu
Applications: WB, B/N, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, ICC
Host: Mouse Monoclonal
Integrin beta 3/CD61 Antibody ...
Integrin beta 3/CD61 Antibody [Unc...
AF2266
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
Integrin beta 3/CD61 Overexpr ...
Integrin beta 3/CD61 Overexpressio...
NBL1-12073
Applications: WB
Proteins
Integrin beta 3/CD61 Recombin ...
Integrin beta 3/CD61 Recombinant P...
NBP1-83453PEP
Species: Hu
Applications: AC
RNAi
Integrin beta 3/CD61 RNAi
Integrin beta 3/CD61 RNAi
H00003690-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Platelet membrane glycoprotein Integrin beta-3 (GP IIIa) forms a Ca2+-dependent heterodimer complex with GP IIb. The GP IIb-IIIa complex constitutes the fibrinogen and fibronectin receptor on stimulated platelets. A biochemically and immunologically similar membrane glycoprotein complex is present on endothelial cells. Homology suggests that GP IIIa is a member of a family of cell-surface adhesion receptors. (1) Data provide further support for the key role of the cytoplasmic domain of the beta3 integrin in cell adhesion and suggest a potential role for the beta3C integrin subunit in modulating cell-matrix interactions (2). It has been demonstrated that the beta 3 subunit of alpha IIb beta 3 was phosphorylated on tyrosine residues in response to thrombin-induced platelet aggregation. Data suggest that tyrosine phosphorylation of an integrin beta subunit may be important in initiating outside-in signaling cascades by inducing association of signaling components directly with the integrin (3). be important in initiating outside-in signaling cascades by inducing association of signaling components directly with the integrin (3).

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Human
Mouse
Product By Gene ID 3690
Alternate Names
  • ITG B3
  • CD61 antigen
  • CD61
  • GP3Aplatelet glycoprotein IIIa
  • GPIIIaintegrin beta-3
  • Platelet membrane glycoprotein IIIa
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

Research Areas for Integrin beta 3/CD61

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytoskeleton Markers
Phospho-Specific
Signal Transduction

PTMs for Integrin beta 3/CD61

Learn more about PTMs related to Integrin beta 3/CD61.

Phosphorylation
Methylation
Demethylation
Cleavage
Acetylation
Dephosphorylation

Bioinformatics Tool for Integrin beta 3/CD61

Discover related pathways, diseases and genes to Integrin beta 3/CD61. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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