Integrin alpha 8 Antibody (481709) [Allophycocyanin]

Images

 
H4 human neuroglioma cell line was stained with Mouse Anti-Human Integrin alpha 8 APC‑conjugated Monoclonal Antibody (Catalog # FAB6194A, filled histogram) or isotype control antibody (Catalog # IC0041A, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
481709
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

Integrin alpha 8 Antibody (481709) [Allophycocyanin] Summary

Immunogen
E. coli-derived recombinant human Integrin alpha 8
Glu610-Leu800
Accession # P53708
Specificity
Detects human Integrin alpha 8 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ITGA8
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha 8 Antibody (481709) [Allophycocyanin]

  • Integrin alpha 8
  • integrin alpha-8
  • integrin, alpha 8
  • ITGA8

Background

Integrin alpha 8 is a 170-200 kDa member of the Integrin family of adhesion molecules. It forms an exclusive noncovalent heterodimer with Integrin beta 1. Integrin alpha 8/ beta 1 promotes both cell adhesion and survival, and is known to bind to fibronectin, LAP-TGF beta 1 and Nephronectin. It is principally expressed in smooth muscle cells.  Human alpha 8 is a 1025 amino acid (aa) type I transmembrane glycoprotein. It contains a 974 aa extracellular domain (ECD) (aa 39-1012) and a 30 aa cytoplasmic domain. In the ECD, human alpha 8 shares 90% aa sequence identity with mouse alpha 8 protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB6194U
Alexa Fluor 405 FAB6194V
Alexa Fluor 488 FAB6194G
Alexa Fluor 532 FAB6194X
Alexa Fluor 594 FAB6194T
Alexa Fluor 647 FAB6194R
Alexa Fluor 700 FAB6194N
Alexa Fluor 750 FAB6194S
Allophycocyanin FAB6194A
Biotin FAB6194B
DyLight 350 FAB6194D
DyLight 405 FAB6194E
DyLight 488 FAB6194K
DyLight 550 FAB6194L
DyLight 594 FAB6194M
DyLight 650 FAB6194W
DyLight 680 FAB6194Y
DyLight 755 FAB6194Z
FITC FAB6194F
Janelia Fluor 549 FAB6194I
Janelia Fluor 646 FAB6194J
PerCP FAB6194C
Phycoerythrin FAB6194P

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Bioinformatics

Gene Symbol ITGA8
Uniprot