IL-3R alpha/CD123 Antibody (107D2.08)


Immunohistochemistry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - IHC staining of Bouin Paraffin section ofhuman invasive breast tumor with107D2.08 (DAB brown)
Flow Cytometry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Facs staining of CD11c-sorted tonsillar cells
Immunohistochemistry-Paraffin: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Paraffin embedded breast cancer tissue sections
Immunohistochemistry-Paraffin: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]
Immunohistochemistry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - IHC staining of frozen humantonsilsection with 106C2.02(Fast Blue)
Flow Cytometry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Human PBMC enriched in monocytes and dendriticcells (Percollgradient) and analyzed by surface flowcytometry

Product Details

Reactivity Hu, CaSpecies Glossary
Applications WB, Flow, IHC, IP
0.5 mg/ml

Order Details

IL-3R alpha/CD123 Antibody (107D2.08) Summary

IL3R Alpha/ CD123 was used as immunogen.
Ion exchange chromatography
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000
Read Publications using
DDX0300P-100 in the following applications:

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
Tris-NaCl (pH 8.0)
No Preservative
0.5 mg/ml
Ion exchange chromatography


This product is manufactured by Dendritics and distributed by Novus Biologicals in North America and other select countries. To order in the following countries: Germany, Finland, United Kingdom, Norway, Denmark, Switzerland, Austria, Japan, and South Korea, please contact Dendritics for additional ordering information.

Alternate Names for IL-3R alpha/CD123 Antibody (107D2.08)

  • CD123 antigen
  • CD123
  • hIL3Ra
  • hIL-3Ra
  • IL-3 R alpha
  • IL-3 receptor subunit alpha
  • IL3R alpha
  • IL-3R alpha
  • IL-3R subunit alpha
  • IL3R
  • IL3RA
  • IL-3Ra
  • IL-3R-alpha
  • IL3RAY
  • IL3RX
  • IL3RY
  • interleukin 3 receptor, alpha (low affinity)
  • interleukin-3 receptor subunit alpha
  • MGC34174


IL3RA (CD123) is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either common beta chain (CDw131) or the IL3RB chain to form high affinity heterodimeric IL3 receptors. CDw131 can complex with the Alpha subunits of the mouse IL3R, IL5R and GMCSFR to form high affinity receptors, while the IL3RB subunit is specific for IL3 but binds with low affinity. IL3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. It is present in Hematopoietic progenitors, basophils, mast cells and megakaryocytes.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IL-3R alpha/CD123 Antibody (DDX0300P-100)(11)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

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Showing Publications 1 - 10 of 11. Show All 11 Publications.
Publications using DDX0300P-100 Applications Species
Pang L, Ng KT, Liu J et al. Plasmacytoid dendritic cells recruited by HIF-1 alpha /eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma Cancer letters 2021-09-16 [PMID: 34536555] (IHC-P, Human) IHC-P Human
Broughton SE et al. Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody. Cell Rep 2014-07-01 [PMID: 25043189]
Koehl U et al. Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol. Front Oncol 2013-05-01 [PMID: 23730623]
Brehm C et al. IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study. PLoS One 2011-01-01 [PMID: 22096557]
Matsuo T et al. Bilateral conjunctival lesions in blastic plasmacytoid dendritic cell neoplasm. J Clin Exp Hematop 2011-01-01 [PMID: 21628861]
Rochereau N et al. Phenotypic localization of distinct DC subsets in mouse Peyer Patch. Vaccine 2011-05-09 [PMID: 21439318]
van de Laar L et al. A nonredundant role for canonical NF-kB in human myeloid dendritic cell development and function. J Immunol 2010-12-15 [PMID: 21076069]
Bachmann M et al. Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1. PLoS Pathog 2010-10-01 [PMID: 20976193]
Tsoukimadou M et al. Isolation of myeloid and plasmacytoid dendritic cells from human bronchoalveolar lavage fluid. Immunol Cell Biol 2006-06-01 [PMID: 16509829]
Treilleux I et al. Dendritic cell infiltration and prognosis of early stage breast cancer. Clin Cancer Res 2004-11-01 [PMID: 15569976]
Show All 11 Publications.

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Gene Symbol IL3RA