IL-18 R beta/IL-1 R7/ACPL Antibody

Western Blot: IL-18 R beta/IL-1 R7/ACPL Antibody [NB100-56433] - Analysis of IL-18 R beta/IL-1 R7/ACPL in A) Human spleen, B) Mouse spleen, and C) Mouse RAW cell lysate using this antibody.

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

IL-18 R beta/IL-1 R7/ACPL Antibody Summary

• Immunogen: A synthetic peptide corresponding to a region within amino acids 50-150 of human IL-18 Receptor accessory protein/IL-18 RA/AcPL was used immunogen.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IL18RAP
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1-3 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for IL-18 R beta/IL-1 R7/ACPL Antibody

• Accessory protein-like
• AcPL
• CD218 antigen-like family member B
• CD218b antigen
• CD218b
• CDw218b
• IL-1 R7
• IL-18 R beta
• IL-18 receptor accessory protein
• IL-18 receptor beta
• IL18R beta
• IL-18RAcP
• IL18RAP
• IL18RB
• IL-18Rb
• IL-18Rbeta
• IL-18R-beta
• IL-1R accessory protein-like
• IL1R7
• IL-1R7
• IL-1R-7
• IL-1RAcPL
• interleukin 18 receptor accessory protein
• Interleukin-1 receptor 7
• interleukin-18 receptor accessory protein
• Interleukin-18 receptor accessory protein-like
• Interleukin-18 receptor beta
• MGC120589
• MGC120590

Background

ACPL is encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IL-18 R beta/IL-1 R7/ACPL Antibody (NB100-56433)(1)

Publication using NB100-56433

• Ho Lien H, Ohno Tatsukuni, Oboki Keisuke et al. IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals. J Leukoc Biol. 2007-12-01 [PMID: 17881510] (Mouse)

Bioinformatics

• Gene Symbol: IL18RAP
• Entrez:
  • 8807(Human)
  • 16174(Mouse)
• Uniprot:
  • O95256()