LNK/SH2B3 Antibody (OTI2D8)

Images

 
Western Blot: LNK Antibody (2D8) [NBP2-00641] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LNK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug ...read more
Immunocytochemistry/ Immunofluorescence: LNK Antibody (2D8) [NBP2-00641] Staining of COS7 cells transiently transfected by pCMV6-ENTRY LNK.
Immunohistochemistry-Paraffin: LNK Antibody (2D8) [NBP2-00641] - Staining of paraffin-embedded Human pancreas tissue using anti-LNK mouse monoclonal antibody.
Flow Cytometry: LNK Antibody (2D8) [NBP2-00641] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-LNK antibody, and then analyzed by ...read more
Immunohistochemistry-Paraffin: LNK Antibody (2D8) [NBP2-00641] - Staining of paraffin-embedded Human Kidney tissue using anti-LNK mouse monoclonal antibody.
Flow Cytometry: LNK Antibody (2D8) [NBP2-00641] - Analysis of Hela cells, using anti-LNK antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Clone
OTI2D8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.37 mg/ml

Order Details

LNK/SH2B3 Antibody (OTI2D8) Summary

Immunogen
Full length human recombinant protein of human SH2B3 (NP_005466) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SH2B3
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150
Theoretical MW
63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
0.37 mg/ml
Purity
Affinity purified

Alternate Names for LNK/SH2B3 Antibody (OTI2D8)

  • IDDM20
  • LNK
  • LNKSH2B adapter protein 3
  • Lymphocyte adapter protein
  • Lymphocyte-specific adapter protein Lnk
  • SH2B adaptor protein 3
  • SH2B3
  • Signal transduction protein Lnk

Background

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for LNK/SH2B3 Antibody (NBP2-00641) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-72514AF350
Alexa Fluor 405 NBP2-72514AF405
Alexa Fluor 488 NBP2-72514AF488
Alexa Fluor 532 NBP2-72514AF532
Alexa Fluor 594 NBP2-72514AF594
Alexa Fluor 647 NBP2-72514AF647
Alexa Fluor 700 NBP2-72514AF700
Alexa Fluor 750 NBP2-72514AF750
Allophycocyanin NBP2-72514APC
Allophycocyanin/Cy7 NBP2-72514APCCY7
Biotin NBP2-72514B
DyLight 350 NBP2-72514UV
DyLight 405 NBP2-72514V
DyLight 488 NBP2-72514G
DyLight 550 NBP2-72514R
DyLight 594 NBP2-72514DL594
DyLight 650 NBP2-72514C
DyLight 680 NBP2-72514FR
DyLight 755 NBP2-72514IR
FITC NBP2-72514F
HRP NBP2-72514H
Janelia Fluor 549 NBP2-72514JF549
Janelia Fluor 646 NBP2-72514JF646
PE NBP2-72514PE
PE/Atto594 NBP2-72514PEATT594
PE/Cy5.5 NBP2-72514PECY55
PE/Cy7 NBP2-72514PECY7
PerCP NBP2-72514PCP

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Bioinformatics Tool for LNK/SH2B3 Antibody (NBP2-00641)

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Bioinformatics

Gene Symbol SH2B3
Entrez