IL-15 Antibody (IL15/7048R)

Immunohistochemistry-Paraffin: IL-15 Antibody (IL15/7048R) [NBP3-13950] - Formalin-fixed, paraffin-embedded human adrenal gland stained with IL-15 antibody (IL15/7048R). HIER: Tris/EDTA, pH9.0, 45min. HRP-polymer, 30min. DAB, 5min.

• Reactivity: Hu
• Applications: IHC
• Clone: IL15/7048R
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

IL-15 Antibody (IL15/7048R) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14100)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Non-hazardous.
  
  Theoretical molecular weight: 14-15kDa
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant fragment of human IL-15 (exact sequence is proprietary) (Uniprot: P40933)
• Localization: Secreted, Cytoplasm, Nuclear
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IL15
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1-2 ug/ml
• Application Notes: Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for IL-15 Antibody (IL15/7048R)

• IL15
• IL-15
• IL-15MGC9721
• interleukin 15
• interleukin-15

Background

IL-15 (14-15 kD) is a member of the four alpha-helical bundle family of cytokines. It is very similar to IL-2, except that IL-15 has an IL-15 alpha receptor subunit. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL15
• Uniprot:
  • P40933()
  • P40933()