HMG-CoA Reductase/HMGCR Antibody (CL0260)

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Orthogonal Strategies: Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617] - Analysis in human liver and skeletal muscle tissues using NBP2-61617 antibody. Corresponding HMGCR ...read more
Genetic Strategies: Western Blot: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617] - Analysis in MCF-7 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-HMGCR antibody. ...read more
Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617] - Staining of human breast cancer shows moderate to strong cytoplasmic positivity in tumor cells.
Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617] - Staining of human liver shows moderate cytoplasmic postivity in hepatocytes.
Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617] - Staining of human fallopian tube shows moderate to strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617] - Staining of human liver cancer shows strong cytoplasmic positivity in tumor cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P, KD
Clone
CL0260
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

HMG-CoA Reductase/HMGCR Antibody (CL0260) Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: GAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTT
Epitope
TLMETHERGVSIRRQ
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HMGCR
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Knockdown Validated
  • Western Blot 1 ug/ml
Application Notes
IHC-Paraffin HIER pH6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for HMG-CoA Reductase/HMGCR Antibody (CL0260)

  • 3-hydroxy-3-methylglutaryl CoA reductase (NADPH)
  • 3-hydroxy-3-methylglutaryl-CoA reductase
  • 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
  • EC 1.1.1
  • EC 1.1.1.34
  • HMG-CoA Reductase
  • HMGCR
  • Hydroxymethylglutaryl-CoA Reductase
  • LDLCQ3

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HMGCR