HMG-CoA Reductase/HMGCR Products

Antibodies
HMG-CoA Reductase/HMGCR Antib ...
HMG-CoA Reductase/HMGCR Antibody
NBP1-91996
Species: Hu, Mu, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HMG-CoA Reductase/HMGCR Antib ...
HMG-CoA Reductase/HMGCR Antibody
46580002
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
HMG-CoA Reductase/HMGCR Antib ...
HMG-CoA Reductase/HMGCR Antibody
NBP1-36961
Species: Hu
Applications: PEP-ELISA, WB (-)
Host: Goat Polyclonal
Lysates
HMG-CoA Reductase/HMGCR Overe ...
HMG-CoA Reductase/HMGCR Overexpres...
H00003156-T01
Species: Hu
Applications: WB
Proteins
HMG-CoA Reductase/HMGCR Recom ...
HMG-CoA Reductase/HMGCR Recombinan...
NBP1-91996PEP
Species: Hu
Applications: AC

Description

HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 3156
Alternate Names
  • LDLCQ3
  • EC 1.1.1
  • EC 1.1.1.34
  • hydroxymethylglutaryl-CoA reductase
  • HMG-CoA reductase
  • 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
  • 3-hydroxy-3-methylglutaryl CoA reductase (NADPH)
  • 3-hydroxy-3-methylglutaryl-CoA reductase

Bioinformatics Tool for HMG-CoA Reductase/HMGCR

Discover related pathways, diseases and genes to HMG-CoA Reductase/HMGCR. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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