FDPS Antibody

Images

 
Western Blot: FDPS Antibody [NBP2-16463] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:3000.
Immunocytochemistry/ Immunofluorescence: FDPS Antibody [NBP2-16463] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: FDPS Antibody [NBP2-16463] - Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using antibody at 1:500 dilution.
Western Blot: FDPS Antibody [NBP2-16463] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE gel, diluted at 1:10000.

Product Details

Summary
Reactivity Hu, Mu, BvSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.75 mg/ml

Order Details

FDPS Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human FDPS. The exact sequence is proprietary.
Localization
Cytoplasm
Predicted Species
Bovine (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FDPS
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Porcine (89%), Rat (89%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.75 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FDPS Antibody

  • 6E)-farnesyl diphosphate synthase
  • Dimethylallyltranstransferase
  • EC 2.5.1.1
  • EC 2.5.1.10
  • farnesyl diphosphate synthaseFPP synthetase
  • farnesyl pyrophosphate synthase
  • farnesyl pyrophosphate synthetase, dimethylallyltranstransferase
  • FPP synthase
  • FPPS
  • FPSgeranyltranstransferase
  • Geranyltranstransferase
  • KIAA1293

Background

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for FDPS Antibody (NBP2-16463) (0)

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Secondary Antibodies

 

Isotype Controls

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Calculators

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Bioinformatics

Gene Symbol FDPS
Uniprot