GnRH Antibody


Immunohistochemistry-Paraffin: GnRH Antibody [NB300-506] - Immunolocalization of GnRH in mouse embryo brain.
Immunohistochemistry-Paraffin: GnRH Antibody [NB300-506] - Analysis of Hyla cinerea (green treefrog) forebrain using GnRH Polyclonal Antibody. Tissues were blocked in 10% normal goat serum in 0.1M PBS and then stained. more

Product Details

Reactivity Mu, AmSpecies Glossary
Applications ICC/IF, IHC, IHC-P
1.0 mg/ml

Order Details

GnRH Antibody Summary

Synthetic peptide: EHWSYGL RPG (Human).
Immunogen affinity purified
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Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS with 1 mg/ml BSA
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


Application Notes
This antibody can be used in Immunofluorescence and Immunohistochemistry-Paraffin. Immunofluorescent staining of GnRH in mouse embryo brain tissue results in staining of neurons in the rostral forebrain. In immunohistochemical procedures, 4% paraformaldehyde is recommended as a fixative. Recommended Starting Dilutions*: IHC: 1 ug/ml Not tested in other applications. *Optimal dilutions should be determined by the end user.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 21303944) ( 25958044).

Alternate Names for GnRH Antibody

  • GNRH
  • GnRH-associated peptide 1
  • gonadotropin-releasing hormone 1 (leutinizing-releasing hormone)
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
  • GRH
  • LHRH
  • LNRH
  • luliberin I
  • Progonadoliberin I
  • progonadoliberin-1
  • prolactin release-inhibiting factor


Gonadotropin releasing hormone (GnRH), also known as luteinizing hormone releasing hormone (LHRH), is a key molecule in the regulation of reproduction in vertebrates. GnRH, a decapeptide, is produced by neurons in the medial basal hypothalamus (MBH) and secreted in a pulsatile manner into the cardiovascular system. The frequency and amplitude of GnRH pulses determine secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary. Higher frequencies (greater than one pulse per hour) stimulate LH secretion while lower frequencies stimulate FSH secretion. The generation of GnRH pulses is effected by numerous stimuli, such as neural, hormonal and environmental. Therefore, behavioral and physiological conditions such as sleep, exercise, and stress can affect the GnRH pulses and cause a disruption of the normal cycle.Recent studies show that GnRH also has a role in mediating cancer. GnRH has been shown to inhibit the growth of human uterine leiomyloma cells by suppressing proliferation and inducing apoptosis. GnRH analogs have been used to treat a wide variety of reproductive cancers, although the side effects of using such compounds are often quite severe.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Product PDFs


Gene Symbol GNRH1

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