GnRH Products

Antibodies
GnRH Antibody
GnRH Antibody
NBP2-22444
Species: Mu, Rt
Applications: IHC, IHC-P, IF
Host: Rabbit Polyclonal
GnRH Antibody
GnRH Antibody
NB300-506
Species: Mu, Am
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GnRH Antibody
GnRH Antibody
NBP1-89749
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
GnRH Overexpression Lysate (D ...
GnRH Overexpression Lysate (Denatu...
H00002796-T01
Species: Hu
Applications: WB
GnRH Overexpression Lysate (N ...
GnRH Overexpression Lysate (Native)
NBP2-10657
Applications: WB
GnRH Overexpression Lysate (N ...
GnRH Overexpression Lysate (Native)
NBP2-11442
Applications: WB
Proteins
GnRH Partial Recombinant Prot ...
GnRH Partial Recombinant Protein
H00002796-Q01
Species: Hu
Applications: WB, ELISA, PA
GnRH Recombinant Protein
GnRH Recombinant Protein
H00002796-P01
Species: Hu
Applications: WB, ELISA, PA
GnRH Recombinant Protein Anti ...
GnRH Recombinant Protein Antigen
NBP1-89749PEP
Species: Hu
Applications: AC
RNAi
GnRH RNAi
GnRH RNAi
H00002796-R01
Species: Hu
GnRH RNAi
GnRH RNAi
H00002796-R02
Species: Hu

Description

Gonadotropin releasing hormone (GnRH), also known as luteinizing hormone releasing hormone (LHRH), is a key molecule in the regulation of reproduction in vertebrates. GnRH, a decapeptide, is produced by neurons in the medial basal hypothalamus (MBH) and secreted in a pulsatile manner into the cardiovascular system. The frequency and amplitude of GnRH pulses determine secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary. Higher frequencies (greater than one pulse per hour) stimulate LH secretion while lower frequencies stimulate FSH secretion. The generation of GnRH pulses is effected by numerous stimuli, such as neural, hormonal and environmental. Therefore, behavioral and physiological conditions such as sleep, exercise, and stress can affect the GnRH pulses and cause a disruption of the normal cycle.Recent studies show that GnRH also has a role in mediating cancer. GnRH has been shown to inhibit the growth of human uterine leiomyloma cells by suppressing proliferation and inducing apoptosis. GnRH analogs have been used to treat a wide variety of reproductive cancers, although the side effects of using such compounds are often quite severe.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Product By Gene ID 2796
Alternate Names
  • LHRH
  • prolactin release-inhibiting factor
  • GRH
  • progonadoliberin-1
  • GNRH
  • luliberin I
  • Progonadoliberin I
  • GnRH-associated peptide 1
  • gonadotropin-releasing hormone 1 (leutinizing-releasing hormone)
  • LNRH
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)

Research Areas for GnRH

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
GPCR

PTMs for GnRH

Learn more about PTMs related to GnRH.

Phosphorylation
Glycosylation
Cleavage
Dephosphorylation

Bioinformatics Tool for GnRH

Discover related pathways, diseases and genes to GnRH. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related GnRH Blog Posts

Check out the latest blog posts on GnRH.
The Use of RNA Polymerase II Antibodies In Proteasome Regulation Studies
At Novus Biologicals, we recently added a new RNA Polymerase II antibody (clone 4H8) to our antibody catalog. RNAPII is an essential transcription enzyme, catalyzing the transcription of DNA during the elongation stage of mRNA synthesis (known as the...    Read more.
Read more GnRH related blogs.