GM-CSF Antibody

Western Blot: GM-CSF Antibody [NBP2-27161] - Analysis of CSF2 in U937 cell lysate in the (1) absence and (2) presence of immunizing peptide using NBP2-27161 at 3 ug/ml. . Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

• Reactivity: Hu, Rt, Pm
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

GM-CSF Antibody Summary

• Description: Novus Biologicals Rabbit GM-CSF Antibody (NBP2-27161) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A portion of amino acids 1-75 of human CSF2 was used as the immunogen.
• Predicted Species: Primate (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CSF2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 3-5ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for GM-CSF Antibody

• colony stimulating factor 2 (granulocyte-macrophage)
• Colony-stimulating factor
• CSF
• CSF2
• CSF-2
• GMCSF
• GM-CSF
• GMCSFgranulocyte-macrophage colony-stimulating factor
• granulocyte-macrophage colony stimulating factor
• MGC131935
• MGC138897
• Molgramostim
• Molgramostin
• Sargramostim

Background

Granulocyte-macrophage colony-stimulating factor (GMCSF2 or CSF2) belongs to theGM-CSF family and is a potent hematopoietic cytokine. CSF2 is an important mediator of inducible haemopoiesis and inflammation, and has a critical role in the function of alveolar macrophages. CSF2 is also reported inthe intermediate promotion of angiogenesis by Toll-like receptor 2/6 as a potential molecule for immune defense and tissue regeneration. Macrophage-activating lipopeptide of 2 kDa (MALP-2), which is a common bacterial lipopeptide induced endothelial cell proliferation and migration and a strong secretion of granulocyte-macrophage colony-stimulating factor (GM-CSF or CSF2). It is reported that CSF2 might be a novel therapeutic agent in neuropathic disease of the eye.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CSF2
• Uniprot:
  • P04141(Human)