GEMIN2 Antibody (SR1523) - BSA Free

Western Blot: GEMIN2 Antibody (SR1523) [NBP3-22356] - Western blot analysis using NBP3-22356 in HepG2 cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IP
• Clone: SR1523
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GEMIN2 Antibody (SR1523) - BSA Free Summary

• Description: Novus Biologicals Rabbit GEMIN2 Antibody (SR1523) - BSA Free (NBP3-22356) is a recombinant monoclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human GEMIN2 (Uniprot #: O14893)
• Specificity: Detects endogenous levels of total GEMIN2
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GEMIN2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
• Theoretical MW: 31 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for GEMIN2 Antibody (SR1523) - BSA Free

• Component of gems 2
• Gemin-2
• GEMIN2survival of motor neuron protein-interacting protein 1
• SIP1-delta
• SMN interacting protein 1-delta
• SMN-interacting protein 1
• survival of motor neuron protein interacting protein 1

Background

SIP1 encodes one of the proteins found in the SMN complex, which consists of the suvival of motor neuron protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GEMIN2