GDF-6/BMP-13 Antibody - BSA Free

Western Blot: GDF-6/BMP-13 Antibody [NBP1-76364] - SK-N-SH lysate with GDF6 antibody at (A) 0.5 and (B) 1 ug/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

GDF-6/BMP-13 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GDF-6/BMP-13 Antibody - BSA Free (NBP1-76364) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human GDF6. The immunogen is located within amino acids 320 - 370 of GDF6. Amino Acid Squence: AFASRHGKRHGKKSRLR
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GDF6
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 0.5-1 ug/ml
• Control Peptide:

  GDF-6/BMP-13 Peptide (NBP1-76364PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for GDF-6/BMP-13 Antibody - BSA Free

• BMP13
• BMP-13
• CDMP2
• GDF16
• GDF6
• GDF-6
• growth differentiation factor 6
• Growth/differentiation factor 16
• growth/differentiation factor 6
• KFS
• KFS1
• KFSL
• MCOP4
• MCOPCB6
• MGC158100
• MGC158101
• SCDO4
• SGM1

Background

Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GDF6
• Uniprot:
  • NP_001001557(Human)