Galectin-2 Antibody - BSA Free

Immunohistochemistry-Paraffin: Galectin-2 Antibody [NBP1-89690] - Staining in human small intestine and cerebral cortex tissues.. Corresponding LGALS2 RNA-seq data are presented for the same tissues.

Immunohistochemistry: Galectin-2 Antibody [NBP1-89690] - Galectin-2 expression in the maternal decidua of control and GDM placentas. Pictures show representative slides for immunohistochemical staining of galectin-2, in the maternal decidua of the control placentas. The scale bar equals 200 um in full size images and 50um in inserts. Black rectangles indicate the section seen at a higher magnification (minuscular letters). Image collected and cropped by CiteAb from the following publication (//www.mdpi.com/1422-0067/21/7/2404), licensed under a CC-BY license.

Immunohistochemistry-Paraffin: Galectin-2 Antibody [NBP1-89690] - Staining of human kidney shows moderate to strong cytoplasmic positivity in cells in tubules.

Immunohistochemistry-Paraffin: Galectin-2 Antibody [NBP1-89690] - Staining of human lymph node shows strong cytoplasmic positivity in non - germinal center cells.

Immunohistochemistry-Paraffin: Galectin-2 Antibody [NBP1-89690] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: Galectin-2 Antibody [NBP1-89690] - Staining of human cerebral cortex shows no positivity in neurons.

Immunohistochemistry: Galectin-2 Antibody [NBP1-89690] - Galectin-2 expression in syncytiotrophoblast (SCT) of control and gestational diabetes mellitus (GDM) placentas. Pictures show representative slides for immunohistochemical staining of galectin-2 in the SCT of the control placentas. The scale bar equals 200 um in full size images and 50um in inserts. Black rectangles indicate the section seen at higher magnification (minuscular letters). Arrow heads show strongly stained fetal endothelial cells. Image collected and cropped by CiteAb from the following publication (//www.mdpi.com/1422-0067/21/7/2404), licensed under a CC-BY license.

Immunohistochemistry: Galectin-2 Antibody [NBP1-89690] - Galectin-2 expression in the maternal decidua of control & GDM placentas. Box & scatter plots (A) showing the IRS for galectin-2 expression in decidua to be significantly higher in GDM placentas (p = 0.001). See Figure 1 for a detailed box plot explanation. Pictures show representative slides for immunohistochemical staining of galectin-2, in the maternal decidua of the control (B) & the GDM (C) placentas. The scale bar equals 200 μm in full size images & 50µm in inserts. Black rectangles indicate the section seen at a higher magnification (minuscular letters). Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/32244351), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunocytochemistry/ Immunofluorescence: Galectin-2 Antibody [NBP1-89690] - Double immunofluorescence phenotyping of villus cells. Nuclei are stained blue using DAPI. Galectin-2, bound by Cy-3-labled secondary antibody, is stained red. CD31, bound by Cy-2-labeled secondary antibody is stained green, marking fetal endothelial cells. Arrows heads indicate the merging expression of CD31 & galectin-2, visible as yellow. The scale bar equals 1 μm. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/32244351), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry: Galectin-2 Antibody [NBP1-89690] - Immunohistochemistry control staining. Colon tissue was used as positive (A, a) as well as negative (B, b) control, for anti-galectin-2-antibody. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/32244351), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunocytochemistry/ Immunofluorescence: Galectin-2 Antibody [NBP1-89690] - Double immunofluorescence phenotyping of decidual cell. Nuclei are stained blue using DAPI. Galectin-2, bound by Cy-3-labled secondary antibody, is stained red. CK7, bound by Cy-2-labeled secondary antibody is stained green, marking the extra-villous trophoblast (EVT) cells. Arrows heads indicate the merging expression of CK7 & galectin-2 visible as yellow. The scale bar equals 1 μm. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/32244351), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Galectin-2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Galectin-2 Antibody - BSA Free (NBP1-89690) is a polyclonal antibody validated for use in IHC. Anti-Galectin-2 Antibody: Cited in 6 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVRGGFNMSSFKL
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LGALS2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Galectin-2 Protein (NBP1-89690PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Galectin-2 Antibody - BSA Free

• Beta-galactoside-binding lectin L-14-II
• GAL2
• Gal-2
• galectin 2
• Galectin2
• Galectin-2
• HL14gal-2
• Lactose-binding lectin 2
• lectin, galactoside-binding, soluble, 2
• LGALS2
• MGC75071
• S-Lac lectin 2

Background

Galectin 2 is encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Galectin-2 Antibody (NBP1-89690)(6)

Publications using NBP1-89690

• Christina Buschmann, Laura Unverdorben, Julia Knabl, Stefan Hutter, Sarah Meister, Susanne Beyer, Maximiliane Burgmann, Alaleh Zati Zehni, Elisa Schmoeckel, Mirjana Kessler, Udo Jeschke, Tanja K Eggersmann, Sven Mahner, Thomas Kolben, Franziska Ganster Placental expression of inflammatory Galectin-12 is associated with gestational diabetes. Journal of reproductive immunology 2024-03-13 [PMID: 38492532]
• Buschmann C, Unverdorben L, Knabl J et al. Galectin-10 Expression in Placentas of Women with Gestational Diabetes Current issues in molecular biology 2023-11-02 [PMID: 37998731] (IHC, Human)
• Schrader S, Unverdorben L, Hutter S et al. Overexpression of galectin-4 in placentas of women with gestational diabetes Journal of reproductive immunology 2022-04-16 [PMID: 35468527] (IF/IHC, Human)
• Hepp P, Unverdorben L, Hutter S et al. Placental Galectin-2 Expression in Gestational Diabetes: A Systematic, Histological Analysis Int J Mol Sci 2020-03-31 [PMID: 32244351] (IF/IHC, Human)
• Hutter S, Knabl J, Andergassen U et al. Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR). Int J Mol Sci 2016-04-07 [PMID: 27070577] (IF/IHC)
• Lindskog C, Asplund A, Engkvist M et al. Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets. Discov Med 2010-06-01 [PMID: 20587347]

Bioinformatics

• Gene Symbol: LGALS2