FXR/NR1H4 Antibody [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 350

FXR/NR1H4 Antibody [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human FXR/NR1H4
  Leu211-Gln486
  Accession # Q96RI1
• Specificity: Detects human FXR/NR1H4 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FXR/NR1H4 Antibody [Alexa Fluor® 350]

• BAR
• bile acid receptor
• farnesoid X receptor
• Farnesoid X-activated receptor
• Farnesol receptor HRR-1
• FXR
• FXRBAR
• HRR-1
• HRR1MGC163445
• NR1H4
• Nuclear receptor subfamily 1 group H member 4
• nuclear receptor subfamily 1, group H, member 4
• Retinoid X receptor-interacting protein 14
• RIP14
• RIP14RXR-interacting protein 14

Background

FXR is a 56 kDa nuclear receptor belonging to the NR1 subfamily. It is highly expressed in liver, intestine, kidney and white adipose tissue. FXR binds bile acids and functions as a transcription activator or repressor through interactions with a large variety of FXR response elements. Human and mouse FXR share approximately 92% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.