Follistatin Antibody (MM0296-9D28) - Azide and BSA Free

Immunohistochemistry-Paraffin: Follistatin Antibody (MM0296-9D28) [NBP2-12313] - 4% PFA fixed and parffine embedded human placental tissue section (4um) is subjected to IHC staining. Tissue was treated with 15ug/ml Protenase K for antige retrieval before IHC is applied.

Product Discontinued

Follistatin Antibody (MM0296-9D28) - Azide and BSA Free Summary

• Immunogen: Human recombinant Follistatin
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: FST
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:20 - 1:100 15ug/ml
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for Follistatin Antibody (MM0296-9D28) - Azide and BSA Free

• follistatin isoform FST317
• Follistatin
• FS
• FSActivin-binding protein
• FST

Background

FST, also known as Follistatin, has a 344 amino acid long isoform that is 38 kDa and a short 317 amino acid that is 35 kDa, functions as an activin antagonist binding directly to it and inhibits the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). Studies of this protein are being performed in relation to polycystic ovary syndrome, pituitary adenoma, insulin resistance, Down syndrome, plasmacytoma, lymphocytic leukemia, pituitary tumor infertility, endometrial carcinoma, teratocarcinoma, azoospermia, meningitis, hepatocellular carcinoma, ovarian carcinoma, liver disease, endometriosis, prostate carcinoma, prostatitis, ovarian cancer, and adenoma. This protein has been also shown to have interactions with ANG, DIP2A, BMP4, FN1, and TXN in signal transduction activin A signaling regulation and TGF-beta signaling pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FST
• Uniprot:
  • P19883()