Human FLRG Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human FLRG Quantikine ELISA Kit Summary

Background
The Quantikine Human FLRG Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human FLRG in cell culture supernates, serum, plasma, urine, and human milk. It contains NS0-expressed recombinant human FLRG and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human FLRG showed linear curves that were parallel to the standard curves obtai...ned using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human FLRG.
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Specificity
Natural and recombinant human FLRG
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
FSTL3

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Interference observed with 1 or more available related molecules.
Publications
Read Publications using DFLRG0.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human FLRG Quantikine ELISA Kit

  • FLRG
  • FLRGFSRP
  • follistatin-like 3 (secreted glycoprotein)
  • Follistatin-like 3
  • Follistatin-like protein 3
  • Follistatin-related gene protein
  • follistatin-related protein 3
  • FSTL3

Background

Follistatin-related gene protein (FLRG) has been shown to bind and inhibit the TGF-beta family ligands including activin, BMP-2, -6, -7, and GDF-8. FLRG is expressed most highly in heart, lung, kidney, and placenta, and is upregulated by TGF-beta and Activin via Smad proteins.
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Follistatin-related Gene Protein/FLRG/Fstl3 (DFLRG0)(8)

We have publications tested in 1 confirmed species: Human.


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Human
(8)
All Species
Showing Publications 1 - 8 of 8.
Publications using DFLRG0 Applications Species
Duan, W;Shi, R;Yang, F;Zhou, Z;Wang, L;Huang, Z;Zang, S; FSTL3 partially mediates the association of increased nonalcoholic fatty liver disease fibrosis risk with acute myocardial infarction in patients with type 2 diabetes mellitus Cardiovascular diabetology 2023-10-30 [PMID: 37904173] (Human) Human
J Luther, AG Vannier, EA Schaefer, RP Goodman The circulating proteomic signature of alcohol-associated liver disease JCI Insight, 2022-07-22;7(14):. 2022-07-22 [PMID: 35866482] (Human) Human
M McAleavy, Q Zhang, PJ Ehmann, J Xu, MF Wipperman, D Ajithdoss, L Pan, M Wakai, R Simonson, A Gadi, A Oyejide, SC Hamon, A Boyapati, LG Morton, T Shavlakadz, CA Kyratsous, DJ Glass The Activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients Molecular and Cellular Biology, 2021-11-01;0(0):MCB0046721. 2021-11-01 [PMID: 34723652] (Human) Human
S Gong, F Gaccioli, J Dopierala, U Sovio, E Cook, PJ Volders, L Martens, PDW Kirk, S Richardson, GCS Smith, DS Charnock-J The RNA landscape of the human placenta in health and disease Nature Communications, 2021-05-11;12(1):2639. 2021-05-11 [PMID: 33976128] (Human) Human
LV Barrios-Si, M Parnell, ZB Shinwari, GA Chaudhary, T Xenofontos, A van Bekhov, S McArthur, BT Elliott Activin subfamily peptides predict chronological age in humans Physiol Rep, 2018-09-01;6(17):e13823. 2018-09-01 [PMID: 30178598] (Human) Human
LM Rice, JC Mantero, EA Stratton, R Warburton, K Roberts, N Hill, RW Simms, R Domsic, HW Farber, R Layfatis Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis Arthritis Res. Ther., 2018-08-16;20(1):185. 2018-08-16 [PMID: 30115106] (Human) Human
AT Amaraseker, B Assadi-Kha, S Liu, M Black, G Dymmott, NM Rogers, AL Sverdlov, JD Horowitz, DTM Ngo Vitamin D supplementation lowers thrombospondin-1 levels and blood pressure in healthy adults PLoS ONE, 2017-05-10;12(5):e0174435. 2017-05-10 [PMID: 28489857] (Human) Human
Naf S, Escote X, Ballesteros M, Yanez R, Simon-Muela I, Gil P, Albaiges G, Vendrell J, Megia A Serum activin A and follistatin levels in gestational diabetes and the association of the Activin A-Follistatin system with anthropometric parameters in offspring. PLoS ONE, 2014-04-24;9(4):e92175. 2014-04-24 [PMID: 24763182] (Human) Human

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Bioinformatics

Gene Symbol FSTL3