FGF-10 Antibody [CoraFluor™ 1]

• Reactivity: Hu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: CoraFluor 1

FGF-10 Antibody [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Produced in rabbits immunized with purified, recombinant Human FGF-10 (Accession#: NP_004456.1; Gln38-Ser208)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FGF10
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen and protein A Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for FGF-10 Antibody [CoraFluor™ 1]

• FGF10
• FGF-10
• fibroblast growth factor 10
• Keratinocyte growth factor 2
• KGF2
• KGF-2
• produced by fibroblasts of urinary bladder lamina propria

Background

The FGF10 gene encodes a 207 amino acid long, 23 kDA fibroblast growth factor 10 protein that is active in embryonic development, cell proliferation, and cell differentiation as it is a member of the fibroblast growth factor family (FGF). Additionally, the FGF10 gene functions in wound healing and is necessary for normal branching morphogenesis. FGF10 participates in regulation of actin cytoskeleton, mitochondrial apoptosis, paxillin interactions, nuclear receptor activation by vitamin-A, downstream signal transduction, and FGFR2 and FGFR ligand binding and activation. It is known to interact with genes FGF1, FGFR2, POMC, FGF18, and FGFBP1. FGF10 is linked to ladd syndrome, intestinal atresia, ectodermal dysplasia, craniosynostosis, cleft lip/palate, clear cell acanthoma, and gilles de la tourette syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FGF10