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251-KG), Recombinant Human Noggin (6057-NG), and Recombinant Human R-Spondin 1 (4645-RS), along with the other reagents listed in the lung organoid expansion medium recipe in the lung organoid culture protocol. Lung organoids were able to differentiate and exhibit markers for various cell types of the lung. Lung organoids were stained with (A) a Rabbit Anti-Human Cytokeratin 5 (KRT5) Monoclonal Antibody (Novus Biologicals, Catalog # NB110-56916; green) and a Goat Anti-Human p63/TP73L Polyclonal Antibody (AF1916; red) to visualize basal cells, (B) a Hamster Anti-Mouse Podoplanin (PDPN) Monoclonal Antibody (Novus Biologicals, Catalog # NB600-1015; green) to visualize alveolar type I cells and a Goat Anti-Human p63/TP73L Polyclonal Antibody (AF1916; red) to visualize basal cells, and (C, D) a Mouse Anti-MUC5AC Monoclonal Antibody (Novus Biologicals, Catalog # NBP2-15196; green) to visualize Goblet cells and a Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (MAB2018; red). All samples were counterstained with DAPI (5748; blue). " class="big_lightbox" target="_blank">
The FGF10 gene encodes a 207 amino acid long, 23 kDA fibroblast growth factor 10 protein that is active in embryonic development, cell proliferation, and cell differentiation as it is a member of the fibroblast growth factor family (FGF). Additionally, the FGF10 gene functions in wound healing and is necessary for normal branching morphogenesis. FGF10 participates in regulation of actin cytoskeleton, mitochondrial apoptosis, paxillin interactions, nuclear receptor activation by vitamin-A, downstream signal transduction, and FGFR2 and FGFR ligand binding and activation. It is known to interact with genes FGF1, FGFR2, POMC, FGF18, and FGFBP1. FGF10 is linked to ladd syndrome, intestinal atresia, ectodermal dysplasia, craniosynostosis, cleft lip/palate, clear cell acanthoma, and gilles de la tourette syndrome.
![Western Blot FGF-10 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/FGF-10_AF6224_Western_Blot_9869.jpg)
![Sandwich ELISA FGF-10 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/FGF-10-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79497-img0001.jpg)
![Bioactivity FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/protein/FGF-10_345-FG_559.jpg)
![Bioactivity FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-bioactivity-215202513491..jpg)
![Immunohistochemistry FGF-10 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/FGF-10_AF6224_Immunohistochemistry_10420.jpg)
![SDS-Page FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/protein/FGF-10_345-FG_557.jpg)
![Bioactivity FGF-10 [Unconjugated]](http://images.novusbio.com/images/345-fg_recombinant-human-fgf-10-protein-bioactivity-2520239220..jpg)
![Bioactivity FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-bioactivity-225202511355..jpg)
![SDS-Page FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-sds-page-215202514167..jpg)
![Binding Activity FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-binding-activity-1172025113412..jpg)
![Surface Plasmon Resonance (SPR) FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-surface-plasmon-resonance-spr-106202581927.jpg)
![Surface Plasmon Resonance (SPR) FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-surface-plasmon-resonance-spr-106202583039.jpg)
![Data FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-2392025155325.jpg)
![Data FGF-10 [Unconjugated]](http://images.novusbio.com/fullsize/bt-fgf10hs_recombinant-human-fgf-10-heat-stable-protein-cf-data-24920257476.jpg)
