ERR beta/NR3B2 Antibody

Images

 
Western Blot: ERR beta/NR3B2 Antibody [NB300-748] - Analysis of ERR beta in HeLa whole cell lysate. Image courtesy of anonymous customer.
Immunocytochemistry/ Immunofluorescence: ERR beta/NR3B2 Antibody [NB300-748] - Analysis of Estrogen Related Receptor beta (green) in NRK cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for ...read more
Western Blot: ERR beta/NR3B2 Antibody [NB300-748] - Analysis of rat kidney.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

ERR beta/NR3B2 Antibody Summary

Immunogen
Synthetic peptide corresponding to residues D(376) Y E L S Q R H E E P R R(388) of mouse ERR2.
Specificity
Estrogen-Related Receptor beta
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ESRRB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:50 - 1:200
  • Western Blot 2 ug/ml
Reviewed Applications
Read 1 Review rated 4
using
NB300-748 in the following applications:

Publications
Read Publication using NB300-748.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 1 mg/ml BSA
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ERR beta/NR3B2 Antibody

  • ERR beta
  • ERR2
  • ESRL2
  • ESRRB
  • estrogen-related receptor beta
  • NR3B2

Background

Estrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extra embryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries. The ligand for the receptor is PPARgamma coactivator 1 (PGC-1) beta.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ERR beta/NR3B2 Antibody (NB300-748)(1)

We have publications tested in 1 application: WB.


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Review for ERR beta/NR3B2 Antibody (NB300-748) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NB300-748:
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WB
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
Western Blot ERR beta/NR3B2 NB300-748
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4
reviewed by:
Verified Customer
WB Human 06/27/2011
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Summary

ApplicationWestern Blot
Sample TestedHela whole cell lysate
SpeciesHuman

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Recent Reviews

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Verified Customer
06/27/2011
Application: WB
Species: Human

Bioinformatics

Gene Symbol ESRRB