ERR gamma/NR3B3 Antibody (H6812)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP, ELISA
Clone
H6812
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Suitable Sample Type
23015

Order Details

ERR gamma/NR3B3 Antibody (H6812) Summary

Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ESRRG
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry 5-15 ug/mL
  • Immunoprecipitation
  • Direct ELISA
Publications
Read Publications using
PP-H6812-00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ERR gamma/NR3B3 Antibody (H6812)

  • DKFZp781L1617
  • ERR gamma
  • ERR gamma-2
  • ERR3
  • ERRG2
  • ERRgamma
  • ESRRG
  • Estrogen receptor-related protein 3
  • estrogen-related receptor gamma
  • FLJ16023
  • KIAA0832
  • NR3B3
  • Nuclear receptor subfamily 3 group B member 3

Background

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Usher's syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ERR gamma/NR3B3 Antibody (PP-H6812-00)(6)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: Cell Culture Treatment, ChIP, Immunoprecipitation, Western Blot.


Filter By Application
Cell Culture Treatment
(1)
ChIP
(1)
Immunoprecipitation
(1)
Western Blot
(3)
All Applications
Filter By Species
Human
(5)
Mouse
(1)
All Species
Showing Publications 1 - 6 of 6.
Publications using PP-H6812-00 Applications Species
LB Sweeney, JB Bikoff, MI Gabitto, S Brenner-Mo, M Baek, JH Yang, EG Tabak, JS Dasen, CR Kintner, TM Jessell Origin and Segmental Diversity of Spinal Inhibitory Interneurons Neuron, 2018;0(0):. 2018 [PMID: 29307712] (Cell Culture Treatment, Mouse) Cell Culture Treatment Mouse
Lee J, Kim E, Kim D, Lee J, Park S, Lee I, Harris R, Lee M, Choi H Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRgamma. PLoS ONE, 2012;7(9):e46324. 2012 [PMID: 23050013] (ChIP, Human) ChIP Human
Kim DK, Kim JR, Koh M, Kim YD, Lee JM, Chanda D, Park SB, Min JJ, Lee CH, Park TS, Choi HS Estrogen-related receptor gamma (ERRgamma) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling. J. Biol. Chem., 2012;286(44):38035-42. 2012 [PMID: 21911493] (Western Blot, Human) Western Blot Human
Xie YB, Park JH, Kim DK, Hwang JH, Oh S, Park SB, Shong M, Lee IK, Choi HS Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. J. Biol. Chem., 2009;284(42):28762-74. 2009 [PMID: 19690166] (Immunoprecipitation, Human) Immunoprecipitation Human
Spector NL, Yarden Y, Smith B, Lyass L, Trusk P, Pry K, Hill JE, Xia W, Seger R, Bacus SS Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells. Proc. Natl. Acad. Sci. U.S.A., 2007;104(25):10607-12. 2007 [PMID: 17556544] (Western Blot, Human) Western Blot Human
Yu S, Wang X, Ng CF, Chen S, Chan FL ERRgamma suppresses cell proliferation and tumor growth of androgen-sensitive and androgen-insensitive prostate cancer cells and its implication as a therapeutic target for prostate cancer. Cancer Res., 2007;67(10):4904-14. 2007 [PMID: 17510420] (Western Blot, Human) Western Blot Human

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol ESRRG