Endoglin/CD105 Antibody (MJ7/18) [DyLight 488]


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Product Details

Reactivity MuSpecies Glossary
Applications WB, Flow, IHC, IHC-Fr, IP
Please see the vial label for concentration. If unlisted please contact technical services.

Endoglin/CD105 Antibody (MJ7/18) [DyLight 488] Summary

Inflamed mouse skin
Endothelial cell selective TGB1 binding molecule-endoglin
Neo-endothelial Cells Marker
IgG2a Kappa
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 488
DyLight 488 (A=493, E=518)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified


Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. Immunohistochemistry-frozen section. It is recommended that the reagent be titrated for optimal performance for each application.

Reactivity Notes



Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Endoglin/CD105 Antibody (MJ7/18) [DyLight 488]

  • CD105 antigen
  • CD105
  • endoglin
  • ENDOsler-Rendu-Weber syndrome 1
  • ENG
  • HHT1FLJ41744
  • ORW
  • ORW1


CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Endoglin/CD105 Antibody (NB100-77666G). (Showing 1 - 2 of 2 FAQ).

  1. I wonder if you have a CD105 or CD34 antibody suitable for IHC that is specific for human and do not bind mouse?
    • We do not have any anti-human CD34 or CD105 antibodies that are confirmed to NOT detect the mouse protein. When we have tested an antibody and confirmed that it will not react with mouse samples, we will add Mu(-) to the datasheet, and unfortunately all of our CD105 and CD34 antibodies will either detect the mouse protein, or they have not been used in mouse samples before.
  2. We are interested in CD105 antibodies that could react with dog, please let me know which products in your catalog you would recommend.
    • We do not currently carry any CD105 antibodies that have been validated for use in dog samples. However, if you are interested in testing any of our CD105 antibodies with dog samples you would be eligible for our Innovators Reward Program, in which you can get a discount voucher for the purchase price of the product. Please contact us at innovators@novusbio.com with any questions regarding this program.

Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-77666APC
DyLight 350 Labeled NB100-77666UV
DyLight 405 Labeled NB100-77666V
DyLight 405LS Labeled NB100-77666V3
DyLight 550 Labeled NB100-77666R
DyLight 650 Labeled NB100-77666C
DyLight 680 Labeled NB100-77666FR
DyLight 755 Labeled NB100-77666IR
PE Labeled NB100-77666PE
PerCP Labeled NB100-77666PCP

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Contact Information

Product PDFs


Gene Symbol ENG

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