Endoglin/CD105 Products

Antibodies
Endoglin/CD105 Antibody [Unco ...
Endoglin/CD105 Antibody [Unconjuga...
Species: Mu
Applications: WB, Simple Western, Flow, IHC, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Endoglin/CD105 Antibody [Unco ...
Endoglin/CD105 Antibody [Unconjuga...
AF1097
Species: Hu
Applications: WB, Flow, IHC, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Antibody Pairs
Endoglin/CD105 Antibody Pair
Endoglin/CD105 Antibody Pair
H00002022-AP11
Species: Hu
Applications: S-ELISA
Endoglin/CD105 Antibody Pair
Endoglin/CD105 Antibody Pair
H00002022-AP21
Species: Hu
Applications: S-ELISA
Endoglin/CD105 Antibody Pair
Endoglin/CD105 Antibody Pair
H00002022-PW2
Species: Hu
Applications: WB, IP
ELISA Kits
Endoglin/CD105 ELISA Kit [Bio ...
Endoglin/CD105 ELISA Kit [Biotin]
KA0442
Species: Hu
Lysates
Endoglin/CD105 Overexpression ...
Endoglin/CD105 Overexpression Lysa...
NBL1-10266
Applications: WB
Endoglin/CD105 Overexpression ...
Endoglin/CD105 Overexpression Lysa...
H00002022-T01
Species: Hu
Applications: WB
Proteins
Endoglin/CD105 Recombinant Pr ...
Endoglin/CD105 Recombinant Protein
NBP2-51541
Species: Hu
Applications: PAGE
Endoglin/CD105 Recombinant Pr ...
Endoglin/CD105 Recombinant Protein...
NBP2-49516PEP
Species: Hu
Applications: AC
Endoglin/CD105 Recombinant Pr ...
Endoglin/CD105 Recombinant Protein...
NBP1-91212PEP
Species: Hu
Applications: AC
RNAi
Endoglin/CD105 RNAi
Endoglin/CD105 RNAi
H00002022-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2022
Alternate Names
  • CD105 antigen
  • ORW1
  • CD105
  • HHT1FLJ41744
  • ENDOsler-Rendu-Weber syndrome 1
  • ORW
  • endoglin

Research Areas for Endoglin/CD105

Find related products by research area and learn more about each of the different research areas below.

Cancer
CD Markers
Cell Biology
Cellular Markers
Endothelial Cell Markers
Extracellular Matrix
Hypoxia
Immunology
Mesenchymal Stem Cell Markers
Stem Cell Markers

Bioinformatics Tool for Endoglin/CD105

Discover related pathways, diseases and genes to Endoglin/CD105. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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