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HAF017). A specific band was detected for Endoglin/CD105 at approximately 90-95 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
CTS008) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank">
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank">
1320-EN) was serially diluted and captured by Rat Anti-Mouse Endoglin/CD105 Monoclonal Antibody (Catalog # MAB13201) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse Endoglin/CD105 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1320) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
HAF017). A specific band was detected for Endoglin/CD105 at approximately 90 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF019). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank">
HAF017). A specific band was detected for Endoglin/CD105 at approximately 90 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
1097-EN) was serially diluted and captured by Mouse Anti-Human Endoglin/CD105 Monoclonal Antibody (Catalog # MAB10972) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human Endoglin/CD105 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1097) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.
![Western Blot Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1320_Western_Blot_18980.jpg)
![Western Blot Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1097_Western_Blot_17307.jpg)
![Sandwich ELISA Endoglin/CD105 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Endoglin-CD105-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79580-img0001.jpg)
![Sandwich ELISA Endoglin/CD105 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Endoglin-CD105-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79452-img0001.jpg)
![N/A Endoglin/CD105 [HRP]](http://images.novusbio.com/fullsize/elisa/DATA_Endoglin_DNDG00_ELISA_774.jpg)
![N/A Endoglin/CD105 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_Endoglin_DY1097_ELISA_1571.jpg)
![N/A Endoglin/CD105 [HRP]](http://images.novusbio.com/fullsize/elisa/DATA_Endoglin_MNDG00_ELISA_1009.jpg)
![Immunocytochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1320_Immunocytochemistry_7258.jpg)
![Immunocytochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1320_Immunocytochemistry_12779.jpg)
![Immunohistochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1320_Immunohistochemistry_9922.jpg)
![Simple Western Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1320_Simple_Western_18976.jpg)
![Immunohistochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1320_mouse-endoglin-cd105-affinity-purified-polyclonal-ab-8220249504646.jpg)
![Immunohistochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1320_mouse-endoglin-cd105-affinity-purified-polyclonal-ab-8220249505921.jpg)
![Immunohistochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1320_mouse-endoglin-cd105-affinity-purified-polyclonal-ab-44202415425096.jpg)
![ELISA Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/af1320_mouse-endoglin-cd105-affinity-purified-polyclonal-ab-elisa-639201852911526776.jpg)
![Immunocytochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1097_Immunocytochemistry_7255.jpg)
![Immunohistochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1097_Immunohistochemistry_7106.jpg)
![Immunohistochemistry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1097_Immunohistochemistry_16085.jpg)
![Simple Western Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1097_Simple_Western_22636.jpg)
![Knockout Validated Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Endoglin_AF1097_Knockout_Validated_22587.jpg)
![Immunocytochemistry/ Immunofluorescence Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1097_human-endoglin-cd105-affinity-purified-polyclonal-ab-4120241032146.jpg)
![Flow Cytometry Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1097_human-endoglin-cd105-affinity-purified-polyclonal-ab-41202410485447.jpg)
![Immunocytochemistry/ Immunofluorescence Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1097_human-endoglin-cd105-affinity-purified-polyclonal-ab-4120241048118.jpg)
![ELISA Endoglin/CD105 Antibody [Unconjugated]](http://images.novusbio.com/images/af1097_human-endoglin-cd105-affinity-purified-polyclonal-ab-elisa-639201854767103884.jpg)
![N/A Endoglin/CD105 [HRP]](http://images.novusbio.com/fullsize/elisa/Endoglin_DNDG00_ELISA_455.jpg)
![N/A Endoglin/CD105 [HRP]](http://images.novusbio.com/fullsize/elisa/Endoglin_MNDG00_ELISA_299.jpg)
