Endoglin/CD105 Antibody (MEM-229)


Flow Cytometry: Endoglin/CD105 Antibody (MEM-229) [NB110-58718] - Analysis of the APC conjugate of this antibody. A cell surface stain was performed on THP-1 cells with Endoglin antibody NB110-58718APC (blue) along with ...read more
Immunofluorescence: Endoglin/CD105 Antibody (MEM-229) [NB110-58718] - Staining of an infarcted porcine heart with anti-CD105 (MEM-229; green); cell nuclei stained with DAPI (blue).

Product Details

Reactivity Hu, PoSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-Fr
1 mg/ml

Endoglin/CD105 Antibody (MEM-229) Summary

recombinant vaccinia virus containing human CD105 (L-isoform) cDNA
Neo-endothelial Cells Marker
This antibody (clone MEM-229) recognizes CD105 (Endoglin), a 180 kDa type I integral membrane homodimer glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy.
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
PBS, pH 7.4
15mM Sodium Azide
1 mg/ml
Protein A purified


Application Notes
Western Blot: use non-reducing conditions.
Read Publications using NB110-58718.

Alternate Names for Endoglin/CD105 Antibody (MEM-229)

  • CD105 antigen
  • CD105
  • endoglin
  • ENDOsler-Rendu-Weber syndrome 1
  • ENG
  • HHT1FLJ41744
  • ORW
  • ORW1


CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Endoglin/CD105 Antibody (NB110-58718)(2)

Showing Publications 1 - 2 of 2.
Publications using NB110-58718 Applications Species
Planka L, Necas A, Srnec R et al. Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs Physiol Res 2009 [PMID:19093735]
Planka L, Necas A, Srnec R et al. Use of allogenic stem cells for the prevention of bone bridge formation in miniature pigs Physiol Res Jul 1 1905 12:00AM

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Endoglin/CD105 Antibody (NB110-58718). (Showing 1 - 2 of 2 FAQs).

  1. I wonder if you have a CD105 or CD34 antibody suitable for IHC that is specific for human and do not bind mouse?
    • We do not have any anti-human CD34 or CD105 antibodies that are confirmed to NOT detect the mouse protein. When we have tested an antibody and confirmed that it will not react with mouse samples, we will add Mu(-) to the datasheet, and unfortunately all of our CD105 and CD34 antibodies will either detect the mouse protein, or they have not been used in mouse samples before.
  2. We are interested in CD105 antibodies that could react with dog, please let me know which products in your catalog you would recommend.
    • We do not currently carry any CD105 antibodies that have been validated for use in dog samples. However, if you are interested in testing any of our CD105 antibodies with dog samples you would be eligible for our Innovators Reward Program, in which you can get a discount voucher for the purchase price of the product. Please contact us at innovators@novusbio.com with any questions regarding this program.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB110-58718AF405
Alexa Fluor (R) 488 Labeled NB110-58718AF488
Alexa Fluor (R) 647 Labeled NB110-58718AF647
Alexa Fluor (R) 700 Labeled NB110-58718AF700
Allophycocyanin Labeled NB110-58718APC
Biotin Labeled NBP1-97565
DyLight 350 Labeled NB110-58718UV
DyLight 405 Labeled NB110-58718V
DyLight 405LS Labeled NB110-58718V3
DyLight 488 Labeled NB110-58718G
DyLight 680 Labeled NB110-58718FR
DyLight 755 Labeled NB110-58718IR
FITC Labeled NB110-81749
PE Labeled NB110-58718PE
PerCP Labeled NB110-58718PCP

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Contact Information

Product PDFs


Gene Symbol ENG

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