DC-SIGN/CD209 Antibody


Western Blot: DC-SIGN/CD209 Antibody [NBP2-27408] - Analysis of DC-SIGN (CD209) in human ThP-1 lysate in the A) absence and B) presence of immunizing peptide and C) mouse RAW lysate using DC-SIGN antibody at 3 ug/ml.

Product Details

Reactivity Hu, Mu, PmSpecies Glossary
Applications WB
0.5 mg/ml

Order Details

DC-SIGN/CD209 Antibody Summary

A portion of amino acids 320-370 from human DC-SIGN (CD209) was used as the immunogen for this antibody.
Dendritic Cell Marker
Protein A purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1 mg antibody in 0.2 ml PBS containing 0.05% BSA.
0.05% Sodium Azide
0.5 mg/ml
Protein A purified

Reactivity Notes

The amino acid sequence used as immunogen for this antibody is 100% homologous in human, ape, and orangutan, 94% in old World monkey, rhesus monkey, macaque, white-cheeked gibbon, and chimpanzee, 89% in rat, and 83% homologous in mouse.

Alternate Names for DC-SIGN/CD209 Antibody

  • CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin
  • CD209 molecule
  • CD209
  • CDSIGNHIV gpl20-binding protein
  • CLEC4L
  • CLEC4LC-type lectin domain family 4 member L
  • DC-SIGN1
  • DC-SIGN1C-type lectin domain family 4, member L
  • DC-SIGNMGC129965
  • Dendritic cell-specific ICAM-3-grabbing non-integrin 1


DC-SIGN, also called CD209, is a C type lectin receptor and an acronym for Dendritic Cell-Specific intracellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin protein. DC-SIGN (CD209) is a 45kDa receptor which binds mannans and glycans on bacteria, viruses and fungi (1). Expressed on Dendritic Cells (DCs) and DC-like macrophages, DC-SIGN is an important cell interaction molecule mediating DC-T cell or DC-Neutrophil responses. DC-SIGN is especially important in DC Th1 interaction, regulating Th1 activity through it's role as a pathogen receptor (2-4). Interaction between DC-SIGN and TLR4 has been demonstrated for induction of inflammatory responses (5). As a CLR and innate immune receptor, DC-SIGN detection and quantitation with antibody probes are used as both a phenotype and indicator of a functional role in anti-microbial responses of DC's.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol CD209

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