DC-SIGN/CD209 Products

Description

The phylogenetically ancient innate immune system governs the initial detection of pathogens and stimulates the first line of host defense. Recognition of pathogens is mediated by phagocytic cells through germline-encoded receptors, known as 'pattern recognition receptors,' which detect pathogen-associated molecular patterns that are characteristic products of microbial physiology. This initial interaction is then translated into a set of endogenous signals that ultimately lead to the induction of the adaptive immune response. The C-type lectin receptors are involved in the primary interface between host and pathogens. Two prototypic members of the C-type lectin-receptor family act as both cell-adhesion receptors and pathogen-recognition receptors: CD209 and its close relative CD209L (MIM 605872) (Barreiro et al., 2005 [PubMed 16252244]).[supplied by OMIM]

Bioinformatics

Product By Gene ID	30835
Alternate Names	CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin CD209 molecule CD209 CDSIGNHIV gpl20-binding protein CLEC4L CLEC4LC-type lectin domain family 4 member L DCSIGN DC-SIGN DC-SIGN1 DC-SIGN1C-type lectin domain family 4, member L DC-SIGNMGC129965 Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Research Areas for DC-SIGN/CD209

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology
Virology, Bacteria and Parasites