CYP7A1 Antibody (946902) [Unconjugated]

Images

 
CYP7A1 was detected in immersion fixed human hepatocytes induced with dexamethasone for 48 hours using Mouse Anti-Human CYP7A1 Polyclonal Antibody (Catalog # MAB9120) at 10 µg/mL for 3 hours at room temperature. ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clone
946902
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price

CYP7A1 Antibody (946902) [Unconjugated] Summary

Immunogen
Human CYP7A1 synthetic peptide
Accession # P22680
Specificity
Detects human CYP7A1 in direct ELISAs.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CYP7A1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry 1-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CYP7A1 Antibody (946902) [Unconjugated]

  • Cholesterol 7-alpha-hydroxylase
  • cholesterol 7-alpha-monooxygenase
  • CP7A
  • CYP7
  • CYP7A1
  • CYP7MGC126826
  • CYPVII
  • Cytochrome P450 7A1
  • cytochrome P450, family 7, subfamily A, polypeptide 1
  • cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase)
  • cytochrome P450, subfamily VIIA polypeptide 1
  • EC 1.14.13
  • EC 1.14.13.17
  • MGC138389
  • polypeptide 1

Background

CYP7A1 (cytochrome P450 7A1; also Cholesterol 7-alph-monooxygenase) is a 504 aa oxidoreductase enzyme (SwissProt #: P22680).  Human CYP7A1 shares 81% and 82% aa identity with mouse and rat CYP7A1, respectively.  It is expressed in the liver where it catalyzes cholesterol metabolism, which is the rate-limiting step in bile acid synthesis.  Disruption of CYP7A1 is associated with high plasma cholesterol levels leading to increased risk of coronary artery disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB400-153
Species: Hu, Mu
Applications: WB, ICC/IF
NBP2-32433
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-46522
Species: Hu
Applications: WB, IHC
NBP2-61616
Species: Hu
Applications: WB, IHC, IHC-P, KD, Simple Western (-)
NBP1-78159
Species: Hu, Rt, Po, Bv
Applications: WB, EM, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vitro, RIA
NBP1-31824
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-27196
Species: Hu, Mu, Bv, Ca, Ch, ChHa, Eq, GP, Pm
Applications: WB, IHC-P
NBP2-29939
Species: Hu
Applications: WB, Flow, IHC-P
NBP2-61816
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC
NBP1-89679
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
NBP1-85691
Species: Hu
Applications: WB, Simple Western, IHC, IHC-P
NB600-582
Species: Hu, Mu, Rt, Ca, Ch, SyHa, Ha
Applications: WB, Simple Western, IHC
NB400-141
Species: Hu, Mu, Ha
Applications: WB, ICC/IF, IP
NBP1-89284
Species: Hu, Po
Applications: WB, ICC/IF, IHC, IHC-P
NB600-41532
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
H00009420-A01
Species: Hu, Mu, Rt
Applications: WB, ELISA
NB300-537
Species: Hu, Mu, Rt, Bv, Rb
Applications: WB, ChIP, Flow, GS, ICC/IF, IHC, IHC-P, IP

Publications for CYP7A1 Antibody (MAB9120) (0)

There are no publications for CYP7A1 Antibody (MAB9120).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CYP7A1 Antibody (MAB9120) (0)

There are no reviews for CYP7A1 Antibody (MAB9120). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for CYP7A1 Antibody (MAB9120) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Array Products

Bioinformatics Tool for CYP7A1 Antibody (MAB9120)

Discover related pathways, diseases and genes to CYP7A1 Antibody (MAB9120). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CYP7A1 Antibody (MAB9120)

Discover more about diseases related to CYP7A1 Antibody (MAB9120).
 

Pathways for CYP7A1 Antibody (MAB9120)

View related products by pathway.

PTMs for CYP7A1 Antibody (MAB9120)

Learn more about PTMs related to CYP7A1 Antibody (MAB9120).

Blogs on CYP7A1

There are no specific blogs for CYP7A1, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Albumin Antibody
NB600-41532

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CYP7A1 Antibody (946902) [Unconjugated] and receive a gift card or discount.

Bioinformatics

Gene Symbol CYP7A1
Entrez
Uniprot