Species: Hu
Applications: ICC/IF
Host: Mouse Monoclonal
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Description
CYP7A1 (cytochrome P450 7A1; also Cholesterol 7-alph-monooxygenase) is a 504 aa oxidoreductase enzyme (SwissProt #: P22680). Human CYP7A1 shares 81% and 82% aa identity with mouse and rat CYP7A1, respectively. It is expressed in the liver where it catalyzes cholesterol metabolism, which is the rate-limiting step in bile acid synthesis. Disruption of CYP7A1 is associated with high plasma cholesterol levels leading to increased risk of coronary artery disease.
Bioinformatics
| Uniprot |
|
| Product By Gene ID |
1581 |
| Alternate Names |
- Cholesterol 7-alpha-hydroxylase
- cholesterol 7-alpha-monooxygenase
- CP7A
- CYP7
- CYP7A1
- CYP7MGC126826
- CYPVII
- Cytochrome P450 7A1
- cytochrome P450, family 7, subfamily A, polypeptide 1
- cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase)
- cytochrome P450, subfamily VIIA polypeptide 1
- EC 1.14.13
- EC 1.14.13.17
- MGC138389
- polypeptide 1
|
![Immunocytochemistry CYP7A1 Antibody (946902) [Unconjugated]](http://images.novusbio.com/fullsize2/CYP7A1_MAB9120_Immunocytochemistry__Immunofluorescence_19938.jpg)
