CXCR5 Antibody - BSA Free

Immunohistochemistry-Paraffin: CXCR5 Antibody [NLS1384] - Human Small Intestine, B-Cell, Burkitt Lymphoma tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: CXCR5 Antibody [NLS1384] - Analysis of anti-CXCR5 antibody with human lymph node, B-cell, mantle cell lymphoma.

Immunohistochemistry-Paraffin: CXCR5 Antibody [NLS1384] - Anti-CXCR5 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: CXCR5 Antibody [NLS1384] - Human Small Intestine, B-Cell, Burkitt Lymphomatissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: CXCR5 Antibody [NLS1384] - Human spleen tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: CXCR5 Antibody [NLS1384] - Lymph node, Mantle Cell lymphoma

• Reactivity: Hu, Pm, Pm, Mu, Rt, Po, Bv, Ca, Ha, Rb
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

CXCR5 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CXCR5.
• Epitope: 3rd cytoplasmic domain
• Localization: Multi-pass membrane protein
• Specificity: Human CXCR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MTA3 (50%).
• Predicted Species: Mouse (94%), Rat (94%), Porcine (94%), Bovine (94%), Rabbit (94%), Hamster (94%), Canine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CXCR5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 - 18 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CXCR5 Antibody - BSA Free

• BLR1
• BLR1MDR-15
• Burkitt lymphoma receptor 1
• Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5)
• Burkitt lymphoma receptor 1, GTP-binding protein
• CD185 antigen
• CD185
• chemokine (C-X-C motif) receptor 5
• C-X-C chemokine receptor type 5
• CXCR5
• CXC-R5
• MDR15CXCR-5
• MGC117347
• Monocyte-derived receptor 15

Background

CXCR5, a Chemokine Receptor, also called Burkitt's lymphoma receptor 1, is required for normal development of Peyer's patches, inguinal lymph nodes, and splenic follicles. CXCR5 binds B-lymphocyte chemoattractant (BLC) and is involved in B-cell homing to follicles in lymph nodes and spleen. Two isoforms are produced by alternative splicing. CXCR5 expression has been reported in human blood and salivary gland and in animal lymphatic organs, blood, bone marrow, brain, liver, lymph node, skin, spleen, stomach, and tonsil. ESTs have been isolated from human brain, germ cell, lung, lymph, pancreas, skin, stomach, and uterus cancer libraries, and from normal human blood, liver/spleen, lymph node, nerve, placenta, small intestine, tonsil, and B-cell/lung/testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CXCR5 Antibody (NLS1384)(1)

Publication using NLS1384

• Pacheco-Rodriguez G, Kumaki F, Steagall WK et al. Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. J Immunol. 2009-02-01 [PMID: 19155472] (IHC-P, Human)
  
  Details:
  IHC(paraffin), human lung tissue, Fig. Supp 1: 1. IMG-71201 (CCR1), Fig. 1D.

Bioinformatics

• Gene Symbol: CXCR5
• Entrez:
  • 643(Human)