CXCR5 Products

Description

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines (2-4). Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation (5,6).

Bioinformatics

Entrez	12145 Mouse 643 Human
Uniprot	NP_001707 Human NP_001707.1 Human P32302 Human
Product By Gene ID	643
Alternate Names	BLR1MDR-15 Burkitt lymphoma receptor 1 Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5) Burkitt lymphoma receptor 1, GTP-binding protein CD185 antigen CD185 chemokine (C-X-C motif) receptor 5 C-X-C chemokine receptor type 5 CXC-R5 MDR15CXCR-5 MGC117347 Monocyte-derived receptor 15

Research Areas for CXCR5

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cytokine Research
GPCR
Immunology
Innate Immunity