Collagen VI Antibody [Biotin] Summary
Collagen Type VI from human and bovine placenta. Uniprot ID P12109
Negligible cross-reactivity with Type I, II, III, IV or V collagens. Non-specific cross reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins is negligible.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store lyophilized antibody at 4C. Aliquot reconstituted liquid and store at -20C. Avoid freeze-thaw cycles.
0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
0.01% Sodium Azide
Immunogen affinity purified
Reconstitute with 100 ul deionized water.
Alternate Names for Collagen VI Antibody [Biotin]
- Collagen 6
- collagen alpha-1(VI) chain
- collagen VI, alpha-1 polypeptide
- collagen, type VI, alpha 1
- human mRNA for collagen VI alpha-1 C-terminal globular domain10alpha 1 (VI) chain (61 AA)
This antibody is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Product General Protocols
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FAQs for Collagen VI Antibody (NB120-6583). (Showing 1 - 1 of 1 FAQ).
Is NB120-6583 made to the full length of the human Collagen Type VI?
- Yes, the immunogen for NB120-6583 was full length Collagen Type VI protein from adult human and bovine tissues.
Positive Control Lysate(s)
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