CD98 Antibody (44D7) - BSA Free

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Flow Cytometry: CD98 Antibody (44D7) [NB600-772] - A surface stain was performed on K562 cells with CD98 (44D7) antibody NB600-772 (blue) and a matched isotype control (orange). Cells were incubated in an antibody ...read more
Flow Cytometry: CD98 Antibody (44D7) [NB600-772] - Staining of human peripheral blood monocytes with mouse anti human CD98, using F(ab')2 rabbit anti mouse IgG: FITC (STAR9B) as a secondary antibody.
Flow Cytometry: CD98 Antibody (44D7) [NB600-772] - Analysis using the FITC conjugate of NB600-772. Staining of human peripheral blood monocytes
Flow Cytometry: CD98 Antibody (44D7) [NB600-772] - Analysis using the PE conjugate of NB600-772. Staining of human peripheral blood monocytes with mouse anti human CD98: RPE.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IP
Clone
44D7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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Catalog# & Formulation Size Price

CD98 Antibody (44D7) - BSA Free Summary

Description
Novus Biologicals Mouse CD98 Antibody (44D7) - BSA Free (NB600-772) is a monoclonal antibody validated for use in IHC, Flow and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
HOON pre-B leukaemia cell line
Localization
Type II membrane protein
Specificity
The reacts with the heavy chain of the CD98 molecule. It binds to all cell lines in culture and to activated T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SLC3A2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
For Flow Cytometry: Use Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
Control
CD98 Overexpression Lysate

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for CD98 Antibody (44D7) - BSA Free

  • 4F2
  • 4F2hc
  • 4T2HC
  • antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC
  • CD98 antigen
  • CD98 heavy chain
  • CD98
  • CD98HC
  • CH98hc
  • FRP-1
  • heavy chain
  • Lymphocyte activation antigen 4F2 large subunit
  • MDU1antigen defined by monoclonal 4F2, heavy chain
  • monoclonal 44D7
  • NACAE4F2 cell-surface antigen heavy chain
  • SLC3A2
  • solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen

Background

The CD98 gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD98 Antibody (NB600-772) (0)

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Product General Protocols

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FAQs for CD98 Antibody (NB600-772). (Showing 1 - 1 of 1 FAQ).

  1. I would like to ask questions about your product, anti-CD98 antibody catalog#NB600-772 and catalog#NBP-03317. Could you tell me why there are two kinds of antibody named the same clone (44D7)? What is the differences between them? If one kind of hybridoma cell produce two kinds of antibody, I cannot figure out this phenomenon.
    • We no longer carry NBP1-03317 as it was discontinued some time ago. We now only carry clone 44D7 under the catalog number NB600-772.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Research Areas for CD98 Antibody (NB600-772)

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Blogs on CD98.

CD98 - cell surface glycoprotein that promotes cell adhesion, growth, and survival
CD98 is a heterodimeric glycoprotein that contains an 80 kDa heavy chain and a 40 kDa light chain. The CD98 heavy chain is also known as the 4F2 antigen heavy chain or FRP-1, and it is encoded by the SLC3A2 gene. The CD98 heavy chain is capable of...  Read full blog post.

xCT: Friend or Foe?
There are two opposing sides to the controversial cysteine/glutamate antiporter. On one hand, it can be viewed a guardian of the cell, protecting it from the damaging oxidative stress that can cause cell death and even cancer. But, conversely, it has ...  Read full blog post.

Glutathione and xCT: Chemoresistance in Tumor Cells
Glutathione, called GSH in its reduced form and GSSG or L(-)-Glutathione in its oxidized form, is an endogenous antioxidant found in most cells in the body. Glutathione's functions include detoxifying xenobiotics from the body, assisting in membrane t...  Read full blog post.

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Bioinformatics

Gene Symbol SLC3A2
Uniprot