SLC7A6 Antibody

Western Blot: SLC7A6 Antibody [NBP2-75086] - taining of Human Heart lysate with antibody at 0.3 ug/mL (35ug protein in RIPA buffer). Detected by chemiluminescence

Immunohistochemistry-Paraffin: SLC7A6 Antibody [NBP2-75086] - Staining of paraffin embedded Human Cerebellum. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

SLC7A6 Antibody Summary

• Description: Novus Biologicals Goat SLC7A6 Antibody (NBP2-75086) is a polyclonal antibody validated for use in IHC, WB and ELISA. Anti-SLC7A6 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-ELDVAEEKKDERKTD, from the C Terminus of the protein sequence according to NP_003974.3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SLC7A6
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/mL
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.3 - 1 ug/mL
• Theoretical MW: 56.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: TBS (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Antigen Affinity-purified

Alternate Names for SLC7A6 Antibody

• Y+L amino acid transporter 2
• LAT2
• LAT-2
• LAT3
• SLC7A6
• solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
• Y+LAT2
• y+LAT-2

Background

SLC7A6 is involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC7A6 Antibody (NBP2-75086)(1)

Publication using NBP2-75086

• Christopher Chidley, Alicia M. Darnell, Benjamin L. Gaudio, Evan C. Lien, Anna M. Barbeau, Matthew G. Vander Heiden, Peter K. Sorger A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments Nature Cell Biology 2024-04-11 [PMID: 38605144]

Bioinformatics

• Gene Symbol: SLC7A6