CD58/LFA-3 Antibody (126) - Azide and BSA Free

Immunohistochemistry-Paraffin: CD58/LFA-3 Antibody (126) [NBP2-90097] - Staining of human CD58 in human tonsil with rabbit monoclonal antibody at 1:200 dilution.

Immunohistochemistry-Paraffin: CD58/LFA-3 Antibody (126) [NBP2-90097] - Staining of human CD58 in human appendix with rabbit monoclonal antibody at 1:200 dilution.

• Reactivity: Hu
• Applications: IHC
• Clone: 126
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CD58/LFA-3 Antibody (126) - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human CD58/LFA-3 (Accession#: AAH05930.1; Met1-Arg215).
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CD58
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100-1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for CD58/LFA-3 Antibody (126) - Azide and BSA Free

• Ag3
• CD58 antigen
• CD58 antigen, (lymphocyte function-associated antigen 3)
• CD58 molecule
• CD58
• FLJ23181
• FLJ43722
• LFA3
• LFA-3
• LFA3ag3
• lymphocyte function-associated antigen 3
• Surface glycoprotein LFA-3

Background

LFA3 is a type 1 transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on most hematopoietic cells and on nonhematopoietic cells such as fibroblasts, endothelial and epithelial cells. Its expression is particularly high on memory T-cells and dendritic cells. LFA3 expression on antigen-presenting cells and target cells enhances T-cells antigen recognition through binding to its ligand, LFA2/CD2, on T-cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD58/LFA-3 Antibody (NBP2-90097)(1)

Publication using NBP2-90097

• Miao B, Hu Z, Mezzadra R et al. CMTM6 shapes antitumor T cell response through modulating protein expression of CD58 and PD-L1 Cancer cell 2023-08-31 [PMID: 37683639] (IHC-P, Human)

Bioinformatics

• Gene Symbol: CD58