Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Protein A or G purified from hybridoma culture supernatant
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CD11c Antibody (ICRF 3.9)
95 alpha chain
95, alpha subunit
CD11 antigen-like family member C
CD11Cleu M5, alpha subunit
Integrin alpha X
integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
integrin, alpha X (complement component 3 receptor 4 subunit)
Leukocyte adhesion glycoprotein p150
Leukocyte adhesion receptor p150
leukocyte surface antigen p150
myeloid membrane antigen, alpha subunit
p150 95 integrin alpha chain
CD11c, also known as Integrin alpha X, is an approximately 150 kDa type I
transmembrane glycoprotein that heterodimerizes with Integrin beta 2, also
known as CD18. The CD11c/CD18 complex, also called CR4 (complement
receptor type 4) is
expressed on macrophages, dendritic cells and hairy cell leukemias, with
lower amounts on other myeloid cells and activated B, NK and some
cytotoxic T cells. It binds fibrinogen and has been reported to be a
receptor for complement component iC3b (1‑3). The human CD11c
extracellular domain (amino acids 20-1107) shares 70 - 76% amino acid
sequence identity with mouse, rat and canine CD11c.
Hogg, N. et al. (1986) Eur. J. Immunol. 16(3):240.
Knapp, W.B. et al. eds. (1989) Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.
Stacker, S.A. and T.A. Springer, J. Immunol. (1991) 146(2):648.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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