CD11c Antibody (ICRF 3.9) [Allophycocyanin]

• Applications: Flow
• Clone: ICRF 3.9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

CD11c Antibody (ICRF 3.9) [Allophycocyanin] Summary

• Immunogen: Rheumatoid synovial fluid cells and human monocyte-derived fibronectin
• Marker: Dendritic Cell Marker
• Specificity: Detects human CD11c.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ITGAX
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Integrin alpha X, also known as CD11c, heterodimerizes with Integrin beta 2, also known as CD18. The CD11c/CD18 complex binds fibrinogen and has been reported to be a receptor for iC3b (1‑3) .

1. Hogg, N. et al. (1986) Eur. J. Immunol. 16(3):240.
2. Knapp, W.B. et al. eds. (1989) Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.
3. Stacker, S.A. and T.A. Springer, J. Immunol. (1991) 146(2):648.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGAX