CD117/c-kit Antibody (YB5.B8) [Biotin] Summary
Hematopoietic Stem Cell Marker
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Flow Cytometry 1:10-1:1000
The YB5.B8 antibody has been tested by flow cytometric analysis of the TF-1 cell line, a human erythroleukemia cell line. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
This antibody is reactive to Human.
Packaging, Storage & Formulations
Store at 4C in the dark.
PBS (pH 7.2) with 0.1% gelatin
0.09% Sodium Azide
Protein A or G purified
Alternate Names for CD117/c-kit Antibody (YB5.B8) [Biotin]
- CD117 antigen
- EC 2.7.10
- EC 188.8.131.52
- piebald trait
- Proto-oncogene c-Kit
- proto-oncogene tyrosine-protein kinase Kit
- SCF R
- SCFRmast/stem cell growth factor receptor
- soluble KIT variant 1
- Tyrosine-protein kinase Kit
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
The YB5.B8 monoclonal antibody reacts with human CD117, also known as c-Kit, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells. When interested in staining HSCs from peripheral blood, we recommend the use of clone 104D2. Please refer to cat..
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Additional CD117/c-kit Products
Bioinformatics Tool for CD117/c-kit Antibody (NBP1-43589)
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Blogs on CD117/c-kit.
Do you see what I see? I c-Kit
The c-Kit (CD117) proto-oncogene is a 145 kD receptor tyrosine kinase family closely related to platelet-derived growth factor receptor (PDGFR). It is a transmembrane receptor and the cellular homolog of the HZ4-feline sarcoma virus transforming gene... Read full blog post.