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CD117/c-kit Products

Antibodies
CD117/c-kit Antibody [Unconju ...
CD117/c-kit Antibody [Unconjugated]
AF1356
CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry CD117/c-kit Antibody [Unconjugated]
HAF017). Specific bands were detected for CD117/c-kit at approximately 135, 150 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot CD117/c-kit Antibody [Unconjugated]
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank"> Simple Western CD117/c-kit Antibody [Unconjugated]
Immunocytochemistry/ Immunofluorescence CD117/c-kit Antibody [Unconjugated]
Immunocytochemistry/ Immunofluorescence CD117/c-kit Antibody [Unconjugated]
Immunocytochemistry/ Immunofluorescence CD117/c-kit Antibody [Unconjugated]
AF1356) at 5 μg/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to cell membrane in esophagus in mouse embryo. " class="big_lightbox" target="_blank"> In-situ Hybridization CD117/c-kit Antibody [Unconjugated]
Flow Cytometry CD117/c-kit Antibody [Unconjugated]
VCTS021). Tissue was stained using the HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109) and counterstained with hematoxylin (blue). Specific staining was localized to the cell membrane and cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry CD117/c-kit Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, Dual ISH-IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 AF1356U-100UG
Alexa Fluor 405 AF1356V-100UG
Alexa Fluor 488 AF1356G-100UG
Alexa Fluor 532 AF1356X-100UG
Alexa Fluor 594 AF1356T-100UG
Alexa Fluor 647 AF1356R-100UG
Alexa Fluor 700 AF1356N-100UG
Alexa Fluor 750 AF1356S-100UG
Alexa Fluor Plus 405 AF1356AFP405-100UG
Alexa Fluor Plus 488 AF1356AFP488-100UG
Alexa Fluor Plus 555 AF1356AFP555-100UG
Alexa Fluor Plus 594 AF1356AFP594-100UG
Alexa Fluor Plus 647 AF1356AFP647-100UG
Alexa Fluor Plus 680 AF1356AFP680-100UG
Allophycocyanin AF1356A
Biotin BAF1356
CoraFluor 1 AF1356CL1
DyLight 350 AF1356D
DyLight 405 AF1356E
DyLight 488 AF1356K
DyLight 550 AF1356L
DyLight 594 AF1356M
DyLight 650 AF1356W
DyLight 680 AF1356Y
DyLight 755 AF1356Z
FITC AF1356F
HRP AF1356H
Janelia Fluor 525 AF1356JF525
Janelia Fluor 549 AF1356I
Janelia Fluor 646 AF1356J
Janelia Fluor 669 AF1356JF669
PE AF1356P
PerCP AF1356C
mFluor Violet 450 SE AF1356MFV450
mFluor Violet 500 SE AF1356MFV500
mFluor Violet 610 SE AF1356MFV610
Formulation Catalog # Availability Price  
Carrier Free AF1356-SP
CD117/c-kit Antibody [Unconju ...
CD117/c-kit Antibody [Unconjugated]
AF332
255-SC) induces cell proliferation in the TF-1 human erythroleukemic cell line in a dose-dependent manner (orange line), as measured by the Resazurin (Catalog # AR002). Under these conditions, proliferation elicited by SCF/c-kit Ligand is neutralized (green line) by increasing concentrations of Goat Anti-Human CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF332). The ND50 is typically 0.06-0.36 µg/mL in the presence of 20 ng/mL of Recombinant Human SCF/c-kit Ligand." class="big_lightbox" target="_blank"> Neutralization CD117/c-kit Antibody [Unconjugated]
CTS013). Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to neurons. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry CD117/c-kit Antibody [Unconjugated]
HAF017). A specific band was detected for CD117/c-kit at approximately 150 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot CD117/c-kit Antibody [Unconjugated]
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank"> Simple Western CD117/c-kit Antibody [Unconjugated]
Immunohistochemistry CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
Western Blot CD117/c-kit Antibody [Unconjugated]
MAB332) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF332) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA CD117/c-kit Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, Flow, IHC, B/N, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 AF332U-100UG
Alexa Fluor 405 AF332V-100UG
Alexa Fluor 488 AF332G-100UG
Alexa Fluor 532 AF332X-100UG
Alexa Fluor 594 AF332T-100UG
Alexa Fluor 647 AF332R-100UG
Alexa Fluor 700 AF332N-100UG
Alexa Fluor 750 AF332S-100UG
Alexa Fluor Plus 405 AF332AFP405-100UG
Alexa Fluor Plus 488 AF332AFP488-100UG
Alexa Fluor Plus 555 AF332AFP555-100UG
Alexa Fluor Plus 594 AF332AFP594-100UG
Alexa Fluor Plus 647 AF332AFP647-100UG
Alexa Fluor Plus 680 AF332AFP680-100UG
Allophycocyanin AF332A
Biotin BAF332
CoraFluor 1 AF332CL1
DyLight 350 AF332D
DyLight 405 AF332E
DyLight 488 AF332K
DyLight 550 AF332L
DyLight 594 AF332M
DyLight 650 AF332W
DyLight 680 AF332Y
DyLight 755 AF332Z
FITC AF332F
HRP AF332H
Janelia Fluor 525 AF332JF525
Janelia Fluor 549 AF332I
Janelia Fluor 646 AF332J
Janelia Fluor 669 AF332JF669
PE AF332P
PerCP AF332C
mFluor Violet 450 SE AF332MFV450
mFluor Violet 500 SE AF332MFV500
mFluor Violet 610 SE AF332MFV610
Formulation Catalog # Availability Price  
Carrier Free AF332-SP
CD117/c-kit Antibody (ACK2) - ...
CD117/c-kit Antibody (ACK2) - BSA ...
NBP1-43359
Immunohistochemistry Whole-Mount CD117/c-kit Antibody (ACK2) - BSA Free
Flow Cytometry CD117/c-kit Antibody (ACK2) - BSA Free
Flow Cytometry CD117/c-kit Antibody (ACK2) - BSA Free
Species: Hu, Mu, Gp
Applications: WB, Flow, ICC/IF, IHC, IP, IHC
Host: Rat Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NBP1-43359AF350
Alexa Fluor 405 NBP1-43359AF405
Alexa Fluor 488 NBP1-43359AF488
Alexa Fluor 532 NBP1-43359AF532
Alexa Fluor 594 NBP1-43359AF594
Alexa Fluor 647 NBP1-43359AF647
Alexa Fluor 700 NBP1-43359AF700
Alexa Fluor 750 NBP1-43359AF750
Alexa Fluor Plus 405 NBP1-43359AFP405
Alexa Fluor Plus 488 NBP1-43359AFP488
Alexa Fluor Plus 555 NBP1-43359AFP555
Alexa Fluor Plus 594 NBP1-43359AFP594
Alexa Fluor Plus 647 NBP1-43359AFP647
Alexa Fluor Plus 680 NBP1-43359AFP680
Allophycocyanin NBP1-43359APC
Allophycocyanin/Cy7 NBP1-43359APCCY7
Biotin NBP1-43359B
CoraFluor 1 NBP1-43359CL1
DyLight 350 NBP1-43359UV
DyLight 405 NBP1-43359V
DyLight 488 NBP1-43359G
DyLight 550 NBP1-43359R
DyLight 594 NBP1-43359DL594
DyLight 650 NBP1-43359C
DyLight 680 NBP1-43359FR
DyLight 755 NBP1-43359IR
FITC NBP1-43359F
HRP NBP1-43359H
Janelia Fluor 525 NBP1-43359JF525
Janelia Fluor 549 NBP1-43359JF549
Janelia Fluor 646 NBP1-43359JF646
Janelia Fluor 669 NBP1-43359JF669
PE NBP1-43359PE
PE/Atto594 NBP1-43359PEATT594
PE/Cy5.5 NBP1-43359PECY55
PE/Cy7 NBP1-43359PECY7
PerCP NBP1-43359PCP
mFluor Violet 450 SE NBP1-43359MFV450
mFluor Violet 500 SE NBP1-43359MFV500
mFluor Violet 610 SE NBP1-43359MFV610
Formulation Catalog # Availability Price  
BSA Free NBP1-43359-0.1mg
BSA Free NBP1-43359-0.05mg
BSA Free NBP1-43359-0.025mg
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We have 47 CD117/c-kit Antibodies
ELISA Kits
Human CD117/c-kit DuoSet ELIS ...
Human CD117/c-kit DuoSet ELISA, 15...
DY332
N/A CD117/c-kit [Biotin]
Species: Hu
Applications: ELISA
Mouse CD117/c-kit ELISA Kit ( ...
Mouse CD117/c-kit ELISA Kit (Color...
NBP3-06959
ELISA Mouse CD117/c-kit ELISA Kit (Colorimetric)
ELISA Mouse CD117/c-kit ELISA Kit (Colorimetric)
Species: Mu
Applications: ELISA
Human Phospho-CD117/c-kit Duo ...
Human Phospho-CD117/c-kit DuoSet I...
DYC3527-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Biotin DYC3527E
Biotin DYC3527-5
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We have 5 CD117/c-kit ELISA Kits
Lysates
CD117/c-kit Overexpression Ly ...
CD117/c-kit Overexpression Lysate
NBP2-11592
Western Blot CD117/c-kit Overexpression Lysate
Species: Hu
Applications: WB
CD117/c-kit Overexpression Ly ...
CD117/c-kit Overexpression Lysate
NBP2-11157
Western Blot CD117/c-kit Overexpression Lysate
Western Blot CD117/c-kit Overexpression Lysate
Species: Hu
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We have 2 CD117/c-kit Lysates
Proteins
Recombinant Human CD117/c-kit ...
Recombinant Human CD117/c-kit Fc B...
BT10961
BT-SCF) with an ED50 of 0.400-4.00 μg/mL." class="big_lightbox" target="_blank"> Binding Activity CD117/c-kit [Biotin]
SDS-Page CD117/c-kit [Biotin]
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Biotin BT10961-050
Formulation Catalog # Availability Price  
Carrier Free BT10961-050
Recombinant Human CD117/c-kit ...
Recombinant Human CD117/c-kit Fc C...
10961-SR
Bioactivity CD117/c-kit [Unconjugated]
SDS-Page CD117/c-kit [Unconjugated]
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free 10961-SR-050
Recombinant Human CD117/c-kit ...
Recombinant Human CD117/c-kit His-...
AVI10931
Binding Activity CD117/c-kit [Biotin]
SDS-Page CD117/c-kit [Biotin]
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Biotin AVI10931-050
Formulation Catalog # Availability Price  
Carrier Free AVI10931-050
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We have 10 CD117/c-kit Proteins

Description

CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with it's ligand is critical for the development of hematopoietic stem cells. The 2B8 antibody does not block c-Kit activity.

Bioinformatics

Entrez
16590
Mouse
3815
Human
64030
Rat
Uniprot
AAH71593.1
Human
NM_000222.2
Human
NP_000213
Human
NP_000213.1
Human
NP_001087241
Human
P05532
Mouse
P10721
Human
P10721
Human
Product By Gene ID 3815
Alternate Names
  • CD117 antigen
  • CD117
  • ckit
  • C-Kit
  • EC 2.7.10
  • EC 2.7.10.1
  • PBT
  • piebald trait
  • Proto-oncogene c-Kit
  • proto-oncogene tyrosine-protein kinase Kit
  • SCFRmast/stem cell growth factor receptor
  • soluble KIT variant 1
  • Tyrosine-protein kinase Kit
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Research Areas for CD117/c-kit

Find related products by research area and learn more about each of the different research areas below.

Cancer
CD Markers
Cellular Markers
Cytokine Research
Hematopoietic Stem Cell Markers
Immunology
Innate Immunity
Mast Cell Markers
Mesenchymal Stem Cell Markers
Phospho-Specific
Protein Kinase
Signal Transduction
Stem Cell Markers
Tyrosine Kinases

Related CD117/c-kit Blog Posts

Check out the latest blog posts on CD117/c-kit.
Do you see what I see? I c-Kit
The c-Kit (CD117) proto-oncogene is a 145 kD receptor tyrosine kinase family closely related to platelet-derived growth factor receptor (PDGFR). It is a transmembrane receptor and the cellular homolog of the HZ4-feline sarcoma virus transforming gene ...    Read more.
Read more CD117/c-kit related blogs.