CD117/c-kit Products

Antibodies
CD117/c-kit Antibody [Unconju ...
CD117/c-kit Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, Dual ISH-IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
CD117/c-kit Antibody [Unconju ...
CD117/c-kit Antibody [Unconjugated]
AF332
Species: Hu
Applications: WB, Simple Western, Flow, IHC, B/N, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
ELISA Kits
Human CD117/c-kit DuoSet ELIS ...
Human CD117/c-kit DuoSet ELISA, 15...
DY332
Species: Hu
Applications: ELISA
Human Phospho-CD117/c-kit Duo ...
Human Phospho-CD117/c-kit DuoSet I...
DYC3527-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Mouse CD117/c-kit ELISA Kit ( ...
Mouse CD117/c-kit ELISA Kit (Color...
NBP3-06959
Species: Mu
Applications: ELISA
Lysates
CD117/c-kit Overexpression Ly ...
CD117/c-kit Overexpression Lysate
NBP2-11592
Species: Hu
Applications: WB
CD117/c-kit Overexpression Ly ...
CD117/c-kit Overexpression Lysate
NBP2-11157
Species: Hu
Proteins
Recombinant Human CD117/c-kit ...
Recombinant Human CD117/c-kit Fc C...
AVI10703
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
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Recombinant Human CD117/c-kit ...
Recombinant Human CD117/c-kit His-...
AVI10931
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Recombinant Human CD117/c-kit ...
Recombinant Human CD117/c-kit Fc C...
10961-SR
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with it's ligand is critical for the development of hematopoietic stem cells. The 2B8 antibody does not block c-Kit activity.

Bioinformatics

Entrez Mouse
Human
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Human
Human
Alternate Names
  • CD117 antigen
  • CD117
  • ckit
  • C-Kit
  • EC 2.7.10
  • EC 2.7.10.1
  • PBT
  • piebald trait
  • Proto-oncogene c-Kit
  • proto-oncogene tyrosine-protein kinase Kit
  • SCFRmast/stem cell growth factor receptor
  • soluble KIT variant 1
  • Tyrosine-protein kinase Kit
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein