CCR3 Antibody

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Western Blot: CCR3 Antibody [NB100-56335] - Analysis using the Azide Free version of NB100-56335. Detection of 10 ug of total cell lysate from Daudi cells with this antibody at 2 ug/ml dilution.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Catalog# & Formulation Size Price

CCR3 Antibody Summary

Immunogen
This antibody was raised against a synthetic peptide of human CCR3 protein.
Specificity
In Daudi, a 45 kDa band should be observed.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCR3
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1-3 ug/ml
Control
CCR3 Lysate (NBL1-08890)
Publications
Read Publication using NB100-56335.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for CCR3 Antibody

  • b-chemokine receptor
  • CC chemokine receptor 3
  • C-C chemokine receptor type 3
  • C-C CKR-3
  • CCR3
  • CCR-3
  • CD193 antigen
  • CD193
  • chemokine (C-C motif) receptor 3
  • CKR3CC-CKR-3CMKBR3CD193
  • eosinophil CC chemokine receptor 3
  • Eosinophil eotaxin receptor
  • MGC102841

Background

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4 (2,3). CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCR3 Antibody (NB100-56335)(1)

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Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol CCR3
Entrez
Uniprot