Mouse CCL24/Eotaxin-2/MPIF-2 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL24/Eotaxin-2/MPIF-2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl24

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL24/Eotaxin-2/MPIF-2 DuoSet ELISA, 15 Plate

• CCL24
• chemokine (C-C motif) ligand 24
• Ckb-6
• Eosinophil chemotactic protein 2
• Eotaxin-2
• member 24
• MPIF2
• MPIF-2
• MPIF2Myeloid progenitor inhibitory factor 2
• MPIF-2Small-inducible cytokine A24
• SCYA24CK-beta-6

Background

Eotaxin-2, also named myeloid progenitor inhibitory factor 2 (MPIF-2), is a member of the CC chemokine subfamily and is designated CCL24. Eotaxin-2 is constitutively expressed in the jejunum and spleen. It can also be induced in the lung by allergen challenge and IL-4. Mouse Eotaxin-2 precursor protein shares approximately 58% amino acid sequence identity with human Eotaxin-2.

Publications for CCL24/Eotaxin-2/MPIF-2 (DY528)(36)

Publications using DY528

• Schaunaman, N;Nichols, T;Cervantes, D;Hartsoe, P;Ferrington, DA;Chu, HW; The Effect of a TLR3 Agonist on Airway Allergic Inflammation and Viral Infection in Immunoproteasome-Deficient Mice Viruses 2024-08-29 [PMID: 39339860] (Mouse, Transgenic Mouse)
• Heyndrickx, I;Deswarte, K;Verstraete, K;Verschueren, KHG;Smole, U;Aegerter, H;Dansercoer, A;Hammad, H;Savvides, SN;Lambrecht, BN; Ym1 protein crystals promote type 2 immunity eLife 2024-01-09 [PMID: 38194250] (Mouse)
• Maggi, L;Camelo, GMA;Rocha, IC;Pereira Alves, W;Moreira, JMP;Almeida Pereira, T;Tafuri, WL;Rabelo, ÉML;Correa, A;Ecco, R;Negrão-Corrêa, DA; Role of the IL-33/ST2 Activation Pathway in the Development of the Hepatic Fibrosis Induced by Schistosoma mansoni Granulomas in Mice International journal of molecular sciences 2023-06-16 [PMID: 37373379] (Mouse)
• E Bandeira, SC Jang, C Lässer, K Johansson, M Rådinger, KS Park Effects of mesenchymal stem cell-derived nanovesicles in experimental allergic airway inflammation Respiratory Research, 2023-01-05;24(1):3. 2023-01-05 [PMID: 36604658] (Mouse)
• SJ Wu, CJ Liou, YL Chen, SC Cheng, WC Huang Fucoxanthin Ameliorates Oxidative Stress and Airway Inflammation in Tracheal Epithelial Cells and Asthmatic Mice Cells, 2021-05-25;10(6):. 2021-05-25 [PMID: 34070405] (Mouse)
• F Botelho, A Dubey, EA Ayaub, R Park, A Yip, A Humbles, R Kolbeck, CD Richards IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M Mediators of Inflammation, 2020-11-28;2020(0):4087315. 2020-11-28 [PMID: 33376451] (Mouse)
• L Ho, A Yip, F Lao, F Botelho, CD Richards RELMalpha is Induced in Airway Epithelial Cells by Oncostatin M Without Requirement of STAT6 or IL-6 in Mouse Lungs In Vivo Cells, 2020-05-27;9(6):. 2020-05-27 [PMID: 32471168] (Mouse, Transgenic Mouse)
• E Boberg, K Johansson, C Malmhäll, J Weidner, M Rådinger House Dust Mite Induces Bone Marrow IL-33-Responsive ILC2s and TH Cells Int J Mol Sci, 2020-05-26;21(11):. 2020-05-26 [PMID: 32466530] (Mouse)
• IS Park, JH Kim, JS Bae, DK Kim, JH Mo The Supernatant of Tonsil-Derived Mesenchymal Stem Cell Has Antiallergic Effects in Allergic Rhinitis Mouse Model Mediators Inflamm., 2020-04-07;2020(0):6982438. 2020-04-07 [PMID: 32322164] (Mouse)
• CL Hsu, KD Chhiba, R Krier-Burr, S Hosakoppal, S Berdnikovs, ML Miller, PJ Bryce Allergic inflammation is initiated by IL-33-dependent crosstalk between mast cells and basophils PLoS ONE, 2020-01-15;15(1):e0226701. 2020-01-15 [PMID: 31940364] (Mouse)
• WC Huang, CY Liu, SC Shen, LC Chen, KW Yeh, SH Liu, CJ Liou Protective Effects of Licochalcone A Improve Airway Hyper-Responsiveness and Oxidative Stress in a Mouse Model of Asthma Cells, 2019-06-20;8(6):. 2019-06-20 [PMID: 31226782] (Mouse)
• DBR Insuela, CT Azevedo, DS Coutinho, NS Magalhães, MR Ferrero, TPT Ferreira, CM Cascabulho, A Henriques-, PC Olsen, BL Diaz, PMR Silva, RSB Cordeiro, MA Martins, VF Carvalho Glucagon reduces airway hyperreactivity, inflammation, and remodeling induced by ovalbumin Sci Rep, 2019-04-24;9(1):6478. 2019-04-24 [PMID: 31019244] (Mouse)
• M Becerra-Dí, AB Strickland, A Keselman, NM Heller Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung Inflammation J. Immunol., 2018-10-10;0(0):. 2018-10-10 [PMID: 30305328] (Mouse)
• EH Lee, M Itan, J Jang, HJ Gu, P Rozenberg, MK Mingler, T Wen, J Yoon, SY Park, JY Roh, CS Choi, WJ Park, A Munitz, Y Jung Eosinophils support adipocyte maturation and promote glucose tolerance in obesity Sci Rep, 2018-07-02;8(1):9894. 2018-07-02 [PMID: 29967467] (Mouse)
• SG Ha, M Dileepan, XN Ge, BN Kang, YG Greenberg, A Rao, G Muralidhar, L Medina-Kau, MA Thompson, CM Pabelick, SM O'Grady, SP Rao, P Sriramarao Knob protein enhances epithelial barrier integrity and attenuates airway inflammation J. Allergy Clin. Immunol., 2018-03-06;0(0):. 2018-03-06 [PMID: 29522849] (ELISA Capture, Mouse)
• Y Ito, N Schaefer, A Sanchez, D Francisco, R Alam, RJ Martin, JG Ledford, C Stevenson, D Jiang, L Li, M Kraft, HW Chu Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice J Innate Immun, 2018-01-27;0(0):. 2018-01-27 [PMID: 29393212] (Mouse)
• C Zhang, W Yi, F Li, X Du, H Wang, P Wu, C Peng, M Luo, W Hua, CC Wong, JJ Lee, W Li, Z Chen, S Ying, Z Ju, H Shen Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis Cell Res., 2018-01-12;0(0):. 2018-01-12 [PMID: 29327730] (Mouse)
• SU Venkatesha, X Zhu, P Rajavelu, R Niranjan, M Manohar, AK Verma, JA Lasky, A Mishra Regulatory effects of Interleukin (IL)-15 on allergen-induced airway obstruction J. Allergy Clin. Immunol., 2017-06-09;0(0):. 2017-06-09 [PMID: 28606589] (Mouse)
• C Li, I Maillet, C Mackowiak, C Viala, F Di Padova, M Li, D Togbe, V Quesniaux, Y Lai, B Ryffel Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells Cell Death Dis, 2017-04-06;8(4):e2735. 2017-04-06 [PMID: 28383552] (Mouse)
• IL-1R1-MyD88 axis elicits papain-induced lung inflammation Eur J Immunol, 2016-09-22;0(0):. 2016-09-22 [PMID: 27569535] (Mouse)
• Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 Proc Natl Acad Sci USA, 2016-07-25;0(0):. 2016-07-25 [PMID: 27457925] (Mouse)
• Tatiana Paula Teixeira Ferreira, Lívia Lacerda Mariano, Roberta Ghilosso-Bortolini, Ana Carolina Santos de de Arantes, Andrey Junior Fernandes, Michelle Berni et al. Potential of PEGylated Toll-Like Receptor 7 Ligands for Controlling Inflammation and Functional Changes in Mouse Models of Asthma and Silicosis Frontiers in Immunology 2016-03-11 [PMID: 27014274] (Mouse)
• Drake L, Iijima K, Hara K, Kobayashi T, Kephart G, Kita H B cells play key roles in th2-type airway immune responses in mice exposed to natural airborne allergens. PLoS ONE, 2015-03-24;10(3):e0121660. 2015-03-24 [PMID: 25803300] (Mouse)
• Mishra , Amarjit, Brown , Alexandr, Yao , Xianglan, Yang , Shutong, Park , Sung-Jun, Liu , Chengyu, Dagur , Pradeep, McCoy , J Philip, Keeran , Karen J, Nugent , Gayle Z, Jeffries , Kenneth, Qu , Xuan, Yu , Zu-Xi, Levine , Stewart, Chung , Jay H Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase. Nat Commun, 2015-02-18;6(0):6224. 2015-02-18 [PMID: 25692509] (Mouse)
• Medina , Jorge L, Coalson , Jacqueli, Brooks , Edward G, Le Saux , Claude J, Winter , Vicki T, Chaparro , Adriana, Principe , Molly F, Solis , Laura, Kannan , T R, Baseman , Joel B, Dube , Peter H Mycoplasma pneumoniae CARDS toxin exacerbates ovalbumin-induced asthma-like inflammation in BALB/c mice. PLoS ONE, 2014-07-24;9(7):e102613. 2014-07-24 [PMID: 25058417] (Mouse)
• Spann K, Loh Z, Lynch J, Ullah A, Zhang V, Baturcam E, Werder R, Khajornjiraphan N, Rudd P, Loo Y, Suhrbier A, Gale M, Upham J, Phipps S IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice. Am J Pathol, 2014-04-13;184(6):1795-806. 2014-04-13 [PMID: 24726644] (Mouse)
• Malmhall C, Alawieh S, Lu Y, Sjostrand M, Bossios A, Eldh M, Radinger M MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung. J Allergy Clin Immunol, 2013-12-24;133(5):1429-38, 1438. 2013-12-24 [PMID: 24373357] (Mouse)
• Kiwamoto T, Brummet M, Wu F, Motari M, Smith D, Schnaar R, Zhu Z, Bochner B Mice deficient in the St3gal3 gene product alpha2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation. J Allergy Clin Immunol, 2013-07-02;133(1):240-7.e1-3. 2013-07-02 [PMID: 23830412] (Mouse)
• Park S, Jing X, Gupta D, Dziarski R Peptidoglycan recognition protein 1 enhances experimental asthma by promoting Th2 and Th17 and limiting regulatory T cell and plasmacytoid dendritic cell responses. J Immunol, 2013-02-18;190(7):3480-92. 2013-02-18 [PMID: 23420883] (Mouse)
• Kottyan LC, Collier AR, Cao KH, Niese KA, Hedgebeth M, Radu CG, Witte ON, Khurana Hershey GK, Rothenberg ME, Zimmermann N Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner. Blood, 2009-07-29;114(13):2774-82. 2009-07-29 [PMID: 19641187] (Mouse)
• Medoff BD, Seung E, Hong S, Thomas SY, Sandall BP, Duffield JS, Kuperman DA, Erle DJ, Luster AD CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. J. Immunol., 2009-01-01;182(1):623-35. 2009-01-01 [PMID: 19109196] (Mouse)
• Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis. Proc. Natl. Acad. Sci. U.S.A., 2008-05-14;105(20):7240-5. 2008-05-14 [PMID: 18480254] (Mouse)
• Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME Surfactant protein D alters allergic lung responses in mice and human subjects. J. Allergy Clin. Immunol., 2008-03-19;121(5):1140-1147.e2. 2008-03-19 [PMID: 18355911] (Mouse)
• Radinger M, Bossios A, Alm AS, Jeurink P, Lu Y, Malmhall C, Sjostrand M, Lotvall J Regulation of allergen-induced bone marrow eosinophilopoiesis: role of CD4+ and CD8+ T cells. Allergy, 2007-12-01;62(12):1410-8. 2007-12-01 [PMID: 17983375] (Mouse)
• Ochkur SI, Jacobsen EA, Protheroe CA, Biechele TL, Pero RS, McGarry MP, Wang H, O'Neill KR, O'Neill KR, Colbert DC, Colby TV, Shen H, Blackburn MR, Irvin CC, Lee JJ, Lee NA Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. J. Immunol., 2007-06-15;178(12):7879-89. 2007-06-15 [PMID: 17548626] (Mouse)
• Fulkerson PC, Fischetti CA, Hassman LM, Nikolaidis NM, Rothenberg ME Persistent effects induced by IL-13 in the lung. Am. J. Respir. Cell Mol. Biol., 2006-04-27;35(3):337-46. 2006-04-27 [PMID: 16645178] (Mouse)

FAQs for CCL24/Eotaxin-2/MPIF-2 (DY528). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: Ccl24