CCR2 Antibody


Western Blot: CCR2 Antibody [NBP1-48337] - Analysis of CCR2 in rat lysate. Image courtesy of product review submitted by Rasha Elbaz.
Immunocytochemistry/ Immunofluorescence: CCR2 Antibody [NBP1-48337] - Analysis of CCR2 in HeLa cells
Immunohistochemistry-Paraffin: CCR2 Antibody [NBP1-48337] - Analysis of FFPE tissue section of human normal breast using 5 ug/ml concentration of CCR2 antibody. The breast ductal/acinar epithelial cells showed a strong more
Immunohistochemistry-Paraffin: CCR2 Antibody [NBP1-48337] - Analysis of FFPE tissue section of human liver cancer using 5 ug/ml concentration of CCR2 antibody. Intense cytoplasmic-membranous immune-staining was observed more
Immunohistochemistry-Paraffin: CCR2 Antibody [NBP1-48337] - Analysis of FFPE tissue section of human rectal adenocarcinoma using 5 ug/ml concentration of CCR2 antibody. The cancerous cells in the section developed a more
Immunohistochemistry-Paraffin: CCR2 Antibody [NBP1-48337] - Analysis of FFPE section of human esophageal squamous cell carcinoma (SCC) using 5 ug/ml concentration of CCR2 antibody. Strong cytoplasmic-membranous more
Immunohistochemistry-Paraffin: CCR2 Antibody [NBP1-48337] - Analysis of FFPE tissue section of human normal kidney using 5 ug/ml concentration of CCR2 antibody. Strong cytoplasmic immunostaining was observed in the more

Product Details

Reactivity Hu, Rt, Fe, PmSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
1 mg/ml

CCR2 Antibody Summary

Synthetic peptide made to an N-terminal portion of the human CCR2 protein (within residues 20-100). [Swiss-Prot# P00338]
Multi-pass cell membrane protein with extracellular and cytoplasmic domains.
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 2 ug/ml
  • Immunocytochemistry/Immunofluorescence 1:50
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
Application Notes
This CCR2 antibody is useful for Flow Cytometry, Immunohistochemistry-Paraffin and Immunocytochemistry/Immunofluorescence applications. Some customers have also reported success using this antibody for Western Blot on rat and human lysates.
Jurkat Lysate (NB800-PC2)
HeLa Lysate (NB800-PC1)
Control Peptide
CCR2 Peptide (NBP1-48337PEP)
Read Publications using
NBP1-48337 in the following applications:

Reactivity Notes

Feline reactivity reported in scientific literature (PMID: 30395163). Reactivity with Rat reported by verified customer. The immunogen sequence similarity with other species: Rhesus monkey and several other primate species (100%), Mouse (69%).

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified

Alternate Names for CCR2 Antibody

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor


CCR2 is a major chemokine receptor expressed on monocytes and its activation through its ligands MCP1, MCP2, MCP3 and MCP4 (systematic names CCL2, CCL8, CCL7 and CCL13, respectively) stimulates the migration of monocytes across the vascular wall into tissues wherein they facilitate chronic inflammation. CCR2 is a member of GPCR1 family and is up-regulated by CREB3. It is a multi-pass membrane protein found in cell membrane, and besides monocytes, it is also found on other cell types like NK cells, macrophages, immature dendritic cells, gamma delta T cells, and activated T cells (including Th17 cells). There are two alternatively spliced forms of CCR2: CCR2A - the major isoform expressed by mononuclear cells and vascular smooth muscle cells; and CCR2B - expressed predominantly by monocytes and activated NK cells. CCR2 has both pro-inflammatory (mediated by APC and T cells) and anti-inflammatory (mediated by regulatory T cells) activities. Besides inflammation, it has been implicated several pathologies including HIV-1/AIDS, autoimmune disorders (psoriasis, rheumatoid arthritis, and multiple sclerosis), pulmonary diseases (asthma, COPD), vascular disease and cancer (prostate cancer).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCR2 Antibody (NBP1-48337)(2)

We have publications tested in 2 confirmed species: Human, Feline.

We have publications tested in 2 applications: ICC/IF, IHC-P.

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Product General Protocols

View specific protocols for CCR2 Antibody (NBP1-48337): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CCR2 Antibody (NBP1-48337). (Showing 1 - 1 of 1 FAQs).

  1. Can you tell if NBP1-48337 could work on mouse tissue? Based on the comparison of the UniProt sequences it is difficult to tell for the 20-100 AA sequence. Could you do a homology check with the real used immunogen and let us know if it would be worth while testing on mouse?
    • The immunogen for this antibody shares 69% similarity with mouse, so it is not predicted to cross-react. However, the immunogen also shares 69% similarity with rat and it has been shown to cross-react with rat by customers, so it may certainly work in mouse as well although it is not predicted. If you would be interested in testing this novel species, please take a look at our Innovator's Reward program.

Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-48337AF405
Alexa Fluor 488 Labeled NBP1-48337AF488
Alexa Fluor 647 Labeled NBP1-48337AF647
Alexa Fluor 700 Labeled NBP1-48337AF700
Biotin Labeled NBP1-48337B
DyLight 405 Labeled NBP1-48337V
DyLight 488 Labeled NBP1-48337G
DyLight 550 Labeled NBP1-48337R
DyLight 650 Labeled NBP1-48337C
FITC Labeled NBP1-48337F
HRP Labeled NBP1-48337H
PE Labeled NBP1-48337PE

Additional Array Products

Bioinformatics Tool for CCR2 Antibody (NBP1-48337)

Discover related pathways, diseases and genes to CCR2 Antibody (NBP1-48337). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CCR2 Antibody (NBP1-48337)

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Pathways for CCR2 Antibody (NBP1-48337)

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PTMs for CCR2 Antibody (NBP1-48337)

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Research Areas for CCR2 Antibody (NBP1-48337)

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Blogs on CCR2.

CCR2 or CD192
CCR2 is a receptor for several monocyte chemoattractant proteins (MCP1, MCP3, MCP4) that specifically govern monocyte chemotaxis. CCR2 transduces its downstream signals through increasing intracellular calcium ion levels. For example, MCP1 regulate...  Read full blog post.

CCR2: Affecting Autoimmunity via MCP1 interactions
CCR2, also known as CD192 (cluster of differentiation 192), is a chemokine receptor and is expressed by monocytes, activated T cells, B cells and natural killer cells. This protein is encoded by CCR2 gene in humans. CCR2 gene encodes two protein isofo...  Read full blog post.

MCP1: One Chemoattractant that's Hard to Resist
Monocyte Chemoattractant Protein (MCP1) is a potent monocyte attractant, is a member of the CC chemokine subfamily. MCP1 exerts its effects through binding to G-protein-coupled receptors on the surface of leukocytes targeted for activation and migrati...  Read full blog post.

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Gene Symbol CCR2