CCR2 Products

Antibodies
Lysates
CCR2 Overexpression Lysate (N ...
CCR2 Overexpression Lysate (Native)
NBP2-09414
Applications: WB
CCR2 Overexpression Lysate (N ...
CCR2 Overexpression Lysate (Native)
NBP2-09004
Applications: WB
CCR2 Overexpression Lysate (N ...
CCR2 Overexpression Lysate (Native)
NBP2-09417
Applications: WB
Proteins
CCR2 Peptide
CCR2 Peptide
NBP1-48337PEP
Species: Hu
CCR2 Peptide
CCR2 Peptide
NBP1-48338PEP
Species: Mu
CCR2 Recombinant Protein
CCR2 Recombinant Protein
H00729230-G01-10ug
Species: Hu
RNAi
CCR2 RNAi
CCR2 RNAi
H00001231-R03
Species: Hu
Applications: RNAi, RNAi SP
CCR2 RNAi
CCR2 RNAi
H00001231-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Bioinformatics

Entrez Human
Human
Mouse
Rat
Uniprot Human
Human
Human
Mouse
Product By Gene ID 729230
Alternate Names
  • CCR2B
  • CD192 antigen
  • CCR2A
  • monocyte chemotactic protein 1 receptor
  • C-C CKR-2
  • MCP-1 receptor
  • CCR-2
  • C-C chemokine receptor type 2
  • Monocyte chemoattractant protein 1 receptor
  • FLJ78302
  • CKR2
  • MGC168006
  • CD192
  • CMKBR2MGC111760
  • MCP-1-RMGC103828
  • CC-CKR-2CKR2B
  • CKR2A
  • chemokine (C-C motif) receptor 2

Research Areas for CCR2

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
GPCR
Immunology
Innate Immunity
Signal Transduction

Bioinformatics Tool for CCR2

Discover related pathways, diseases and genes to CCR2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related CCR2 Blog Posts

Check out the latest blog posts on CCR2.
CCR2 or CD192
CCR2 is a receptor for several monocyte chemoattractant proteins (MCP1, MCP3, MCP4) that specifically govern monocyte chemotaxis. CCR2 transduces its downstream signals through increasing intracellular calcium ion levels. For example, MCP1 regulate...    Read more.
CCR2: Affecting Autoimmunity via MCP1 interactions
CCR2, also known as CD192 (cluster of differentiation 192), is a chemokine receptor and is expressed by monocytes, activated T cells, B cells and natural killer cells. This protein is encoded by CCR2 gene in humans. CCR2 gene encodes two protein isofo...    Read more.
MCP1: One Chemoattractant that's Hard to Resist
Monocyte Chemoattractant Protein (MCP1) is a potent monocyte attractant, is a member of the CC chemokine subfamily. MCP1 exerts its effects through binding to G-protein-coupled receptors on the surface of leukocytes targeted for activation and migrati...    Read more.
Read more CCR2 related blogs.