Carbonic Anhydrase IX/CA9 Antibody (66.4.C2 (PN-15)) [PerCP]

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Summary
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    • Catalog Number
      NBP2-33152PCP
    • Availability
      Product Discontinued

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Carbonic Anhydrase IX/CA9 Antibody (66.4.C2 (PN-15)) [PerCP] Summary

Immunogen
Fresh, normal human renal cortical tissue homogenate was used as immunogen to generate the RCC antibody.
Localization
Cell surface and cytoplasmic
Specificity
Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CA9
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1-5ug/ml for coating
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Carbonic Anhydrase IX/CA9 Antibody (66.4.C2 (PN-15)) [PerCP]

  • CA9
  • CA-IX
  • CAIXcarbonic anhydrase 9
  • Carbonate dehydratase IX
  • Carbonic Anhydrase IX
  • carbonic anhydrase IXpMW1
  • carbonic dehydratase
  • EC 4.2.1.1
  • G250
  • Membrane antigen MN
  • MN
  • MNRCC-associated antigen G250
  • P54/58N
  • RCC
  • RCC-associated protein G250
  • Renal cell carcinoma-associated antigen G250

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Renal Cell Carcinoma (gp200) Antibody (NBP2-33152PCP) (0)

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Bioinformatics Tool for Renal Cell Carcinoma (gp200) Antibody (NBP2-33152PCP)

Discover related pathways, diseases and genes to Renal Cell Carcinoma (gp200) Antibody (NBP2-33152PCP). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Renal Cell Carcinoma (gp200) Antibody (NBP2-33152PCP)

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PTMs for Renal Cell Carcinoma (gp200) Antibody (NBP2-33152PCP)

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Blogs on Carbonic Anhydrase IX/CA9.

Carbonic anhydrase IX (CAIX) - a reliable histochemical marker of hypoxia
Carbonic anhydrase IX is a member of the carbonic anhydrase family. This family consists of catalytic enzymes capable of converting carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. This family of molecules is abundantly e...  Read full blog post.

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Bioinformatics

Gene Symbol CA9