Western Blot: BRIP1/FANCJ Antibody [NBP1-31883] - Sample (30 ug of whole cell lysate) A: Hela 5% SDS PAGE FANCJ antibody, antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: BRIP1/FANCJ Antibody [NBP1-31883] - 293T cells were fixed in 2% paraformaldehyde/culture medium at 37 degrees C for 30 min. Green: BRIP1 protein stained by FANCJ antibody ...read more
Mouse reactivity reported in scientific literature (PMID: 26490168)
Alternate Names for BRIP1/FANCJ Antibody
ATP-dependent RNA helicase BRIP1
BACH1BRCA1/BRCA2-associated helicase 1
BRCA1 interacting protein C-terminal helicase 1
BRCA1-associated C-terminal helicase 1
BRCA1-binding helicase-like protein BACH1
BRCA1-interacting protein 1
BRCA1-interacting protein C-terminal helicase 1
FANCJFanconi anemia group J protein
BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.