Species: Hu, Mu
Applications: WB, Simple Western, Func, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The Fanconi anemia group subunit J protein (FANCJ), also called BRIP1 or BACH1, is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. Defects in FANCJ cause the autosomal recessive disorder, Fanconi anemia. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation.
FANCG antibodies are useful for DNA repair studies and cell cycle research.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
83990 |
| Alternate Names |
- ATP-dependent RNA helicase BRIP1
- BACH1BRCA1/BRCA2-associated helicase 1
- BRCA1 interacting protein C-terminal helicase 1
- BRCA1-associated C-terminal helicase 1
- BRCA1-binding helicase-like protein BACH1
- BRCA1-interacting protein 1
- BRCA1-interacting protein C-terminal helicase 1
- EC 3.6.1
- EC 3.6.4.13
- FANCJFanconi anemia group J protein
- FLJ90232
- MGC126521
- MGC126523
- OF
- Protein FACJ
|
