BRIP1/FANCJ Products

Description

The Fanconi anemia group subunit J protein (FANCJ), also called BRIP1 or BACH1, is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. Defects in FANCJ cause the autosomal recessive disorder, Fanconi anemia. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation.

FANCG antibodies are useful for DNA repair studies and cell cycle research.

Bioinformatics

Entrez	83990 Human
Uniprot	NM_032043 Human NP_114432 Human Q9BX63 Human
Product By Gene ID	83990
Alternate Names	ATP-dependent RNA helicase BRIP1 BACH1BRCA1/BRCA2-associated helicase 1 BRCA1 interacting protein C-terminal helicase 1 BRCA1-associated C-terminal helicase 1 BRCA1-binding helicase-like protein BACH1 BRCA1-interacting protein 1 BRCA1-interacting protein C-terminal helicase 1 EC 3.6.1 EC 3.6.4.13 FANCJFanconi anemia group J protein FLJ90232 MGC126521 MGC126523 OF Protein FACJ

Research Areas for BRIP1/FANCJ

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Chromatin Research
DNA Double Strand Break Repair
DNA Repair
Genes Sensitive to DNA Damaging Agents
Phospho-Specific