Frataxin Antibody (10E11)

Western Blot: Frataxin Antibody (10E11) [NBP2-59478] - Lane 1: 293T cell lysates, Lane 2: Frataxin transfected 293T cell lysates

Immunocytochemistry/Immunofluorescence: Frataxin Antibody (10E11) [NBP2-59478] - Analysis of Frataxin in A549 cell line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human Frataxin antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

• Reactivity: Hu
• Applications: WB, ELISA, Flow, ICC/IF
• Clone: 10E11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

Frataxin Antibody (10E11) Summary

• Immunogen: Recombinant human Frataxin (42-210aa) purified from E. coli
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FXN
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence 1:100

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Frataxin Antibody (10E11)

• CyaY
• EC 1.16.3.1
• FA
• FARRmitochondrial
• frataxin
• Friedreich ataxia protein
• Friedreich ataxia
• Fxn
• X25MGC57199

Background

Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FXN