BMP-2/BMP-4 Antibody (65529) [PE]

• Reactivity: Hu
• Applications: WB
• Clone: 65529
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PE

BMP-2/BMP-4 Antibody (65529) [PE] Summary

• Immunogen: E. coli-derived recombinant human BMP-2
  Ala284-Arg396
  Accession # P12643
• Specificity: Detects human BMP-2 and human BMP-4 in direct ELISAs and Western blots. In direct ELISAs, this antibody shows no cross‑reactivity with recombinant human (rh) BMP-5 or rhBMP-6.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: BMP2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for BMP-2/BMP-4 Antibody (65529) [PE]

• BDA2
• BMP-2
• BMP-2/BMP-4
• BMP2A
• BMP-2A
• BMP2ABone morphogenetic protein 2A
• bone morphogenetic protein 2

Background

BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. BMP2 and 4 are members of the TGF-beta family, consisting of disulfide-linked homodimers. Both interact with GREM2 and SOSTDC1 and induce bone and cartilage formation. BMP4 also acts in mesoderm induction, tooth development, limb formation and fracture repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMP2