Sort By:

Products (5)

page of 1

BMP-2/BMP-4 Antibodies

We offer BMP-2/BMP-4 Antibodies for use in common research applications: Immunocytochemistry, Immunohistochemistry, Neutralization, Western Blot. Each BMP-2/BMP-4 Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our BMP-2/BMP-4 Antibodies can be used in a variety of model species: Human, Zebrafish. Use the list below to choose the BMP-2/BMP-4 Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Choose from our BMP-2/BMP-4 polyclonal antibodies and browse our BMP-2/BMP-4 monoclonal antibody catalog.

Alternate Names for BMP-2/BMP-4 Antibodies

anti-BMP-2/BMP-4 antibody, anti-BMP2 antibody, anti-BDA2 antibody, anti-BMP-2 antibody, anti-BMP-2A antibody, anti-BMP2A antibody, anti-BMP2ABone morphogenetic protein 2A antibody, anti-bone morphogenetic protein 2 antibody

5 Results for "bmp-2-bmp-4" in Primary Antibodies

MAB3552

BMP-2/BMP-4 Antibody (100230) [Unconjugated]

(16 Publications)

100 μg

MAB3552

Recombinant Human BMP‑2 (Catalog # 355-BM) induces alkaline phosphatase production in the the ATDC5 mouse chondrogenic cell line in a dose-dependent manner (orange line). Alkaline Phosphatase Production elicited by Recombinant Human BMP‑2 (1 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human BMP-2/BMP-4 Monoclonal Antibody (Catalog # MAB3552). The ND50 is typically 5-15 µg/mL in the presence of heparin (2 µg/mL).

Effects of neutralization of BMP2 and BMP4 on xenografted tumor growth induced by DragonCMT93 cells with or without Dragon over-expression were injected into C57BL/6 mice, followed by intraperitoneal injection of 2 μg/body weight of BMP2/4 antibody or IgG1 once every 2 days from the day of cell injection to 22 days after cell injection. A.Xenografted tumors were isolated from mice at 22 days after cell injection. B. The sizes of xenografted tumors were measured at days 7, 10, 13, 16 19 and 22 after cell injection (n = 6). P < 0.05, oeDra+anti-BMP2/4 vs oeDra+IgG. C. Representative images from Micro-PET/CT performed on mice at day 20 after cell injection: white circular outlines indicate xenografted tumors; arrows indicate SUV-MAX absorbance. D. Tumor volumes and SUV-MAX absorbance are quantified by Micro-PET/CT at day 20 after cell injection (n = 6). E. Phosphorylation levels of Erk1/2 and Smad1/5/8 in tumors collected at day 22 after cell injections (upper panel, Western blots; lower panel, densitometric analysis). F. Schematic diagram depicting Dragon action in regulating proliferation in colon cancer cells. Dragon/BMPs activate the Smad1/5/8 and Erk1/2 pathways via a mechanism yet to be determined and then promote colon cancer cell proliferation and tumor growth. *P < 0.05, **P < 0.01. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/26029998), licensed under a CC-BY license. Not internally tested by R&D Systems.

Transcriptional regulation of IRX3 and IRX5. (A) RQ-PCR analysis of HOXA10 in AML cell lines (left). Transcript levels are indicated in relation to OCI-AML3, and IRX3/IRX5-positive cell lines are indicated in red. RQ-PCR analysis of OCI-AML3 (above) and MEGAL (below) showed downregulation of IRX3 and IRX5 after siRNA-mediated knockdown of HOXA10 (right). (B) RQ-PCR analysis of BMP2 in AML cell lines (left). Transcript levels are indicated in relation to OCI-AML3. ELISA results for BMP2 protein levels in AML cell line supernatants are inserted. RQ-PCR analysis of OCI-AML3 treated with BMP2 resulted in the upregulation of IRX3 and IRX5 (right). (C) RQ-PCR analysis of OCI-AML3 after siRNA-mediated knockdown of JUNB (left) and SMAD4 (right) showed downregulation of IRX3 and IRX5. (D) RQ-PCR analysis of JUNB in AML cell lines (left). Transcript levels are indicated in relation to OCI-AML3. RQ-PCR analysis of OCI-AML3 treated with inhibitory BMP2-antibody resulted in downregulation of JUNB, IRX3, and IRX5, while HOXA10 was not significantly affected (right). p-values are indicated by asterisks (* p < 0.05, ** p < 0.01, *** p < 0.001, n.s. not significant). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/35328612), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

,

Applications: ,

Host:

Mouse Monoclonal

Host: Mouse Monoclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB3552U-100UG
Alexa Fluor 405	FAB3552V-100UG
Alexa Fluor 488	FAB3552G-100UG
Alexa Fluor 532	FAB3552X-100UG
Alexa Fluor 594	FAB3552T-100UG
Alexa Fluor 647	FAB3552R-100UG
Alexa Fluor 700	FAB3552N-100UG
Alexa Fluor 750	FAB3552S-100UG
Allophycocyanin	FAB3552A
Biotin	BAM3552
CoraFluor 1	FAB3552CL1
DyLight 350	FAB3552D
DyLight 405	FAB3552E
DyLight 488	FAB3552K
DyLight 550	FAB3552L
DyLight 594	FAB3552M
DyLight 650	FAB3552W
DyLight 680	FAB3552Y
DyLight 755	FAB3552Z
FITC	FAB3552F
HRP	FAB3552H
Janelia Fluor 525	FAB3552JF525
Janelia Fluor 549	FAB3552I
Janelia Fluor 646	FAB3552J
Janelia Fluor 669	FAB3552JF669
PE	FAB3552P
PerCP	FAB3552C
mFluor Violet 450 SE	FAB3552MFV450
mFluor Violet 500 SE	FAB3552MFV500
mFluor Violet 610 SE	FAB3552MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	MAB3552-SP
Carrier Free	MAB3552-500

compare

(select up to 3 products from this page to compare)

AF355

BMP-2/BMP-4 Antibody [Unconjugated]

(9 Publications)

100 μg

AF355

BMP‑2/BMP‑4 was detected in immersion fixed paraffin-embedded sections of human lung cancer using Goat Anti-Human BMP‑2/BMP‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF355) at 0.5 µg/ml for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the cytoplasm. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

,

Applications: ,

Host:

Goat Polyclonal

Host: Goat Polyclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	AF355U-100UG
Alexa Fluor 405	AF355V-100UG
Alexa Fluor 488	AF355G-100UG
Alexa Fluor 532	AF355X-100UG
Alexa Fluor 594	AF355T-100UG
Alexa Fluor 647	AF355R-100UG
Alexa Fluor 700	AF355N-100UG
Alexa Fluor 750	AF355S-100UG
Allophycocyanin	AF355A
Biotin	BAF355
CoraFluor 1	AF355CL1
DyLight 350	AF355D
DyLight 405	AF355E
DyLight 488	AF355K
DyLight 550	AF355L
DyLight 594	AF355M
DyLight 650	AF355W
DyLight 680	AF355Y
DyLight 755	AF355Z
FITC	AF355F
HRP	AF355H
Janelia Fluor 525	AF355JF525
Janelia Fluor 549	AF355I
Janelia Fluor 646	AF355J
Janelia Fluor 669	AF355JF669
PE	AF355P
PerCP	AF355C
mFluor Violet 450 SE	AF355MFV450
mFluor Violet 500 SE	AF355MFV500
mFluor Violet 610 SE	AF355MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	AF355-SP

compare

(select up to 3 products from this page to compare)

MAB355

BMP-2/BMP-4 Antibody (65529)

(2 Publications)

100 μg

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

Applications:

Host:

Mouse Monoclonal

Host: Mouse Monoclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB355U-100UG
Alexa Fluor 405	FAB355V-100UG
Alexa Fluor 488	FAB355G-100UG
Alexa Fluor 532	FAB355X-100UG
Alexa Fluor 594	FAB355T-100UG
Alexa Fluor 647	FAB355R-100UG
Alexa Fluor 700	FAB355N-100UG
Alexa Fluor 750	FAB355S-100UG
Allophycocyanin	FAB355A
Biotin	FAB355B
CoraFluor 1	FAB355CL1
DyLight 350	FAB355D
DyLight 405	FAB355E
DyLight 488	FAB355K
DyLight 550	FAB355L
DyLight 594	FAB355M
DyLight 650	FAB355W
DyLight 680	FAB355Y
DyLight 755	FAB355Z
FITC	FAB355F
HRP	FAB355H
Janelia Fluor 525	FAB355JF525
Janelia Fluor 549	FAB355I
Janelia Fluor 646	FAB355J
Janelia Fluor 669	FAB355JF669
PE	FAB355P
PerCP	FAB355C
mFluor Violet 450 SE	FAB355MFV450
mFluor Violet 500 SE	FAB355MFV500
mFluor Violet 610 SE	FAB355MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	MAB355-SP
Carrier Free	MAB355-500

compare

(select up to 3 products from this page to compare)

NBP3-12507

BMP-2/BMP-4 Antibody

100 μg

NBP3-12507

Western Blot: BMP-2/BMP-4 Antibody [NBP3-12507] - Axolotl tails

Immunohistochemistry-Paraffin: BMP-2/BMP-4 Antibody [NBP3-12507] - Mouse embryo. 1:50 in IHC blocking buffer.

Western Blot: BMP-2/BMP-4 Antibody [NBP3-12507] - 1. Mouse spleen. 2. Mouse brain. Apparent MW is 47 KDa. 1:250 dilution in DilOBuffer.

Western Blot: BMP-2/BMP-4 Antibody [NBP3-12507] - 1:500 antibody dilution in DiluObuffer. Apparent MW is 52 KDa.

Immunohistochemistry-Paraffin: BMP-2/BMP-4 Antibody [NBP3-12507] - Mouse embryo. 1:50 dilution. in IHC blocking buffer.

Reactivity:

Hu, Mu, Rt

Species Glossary

Reactivity: Hu, Mu, Rt

Applications:

, , ,

Applications: , , ,

Host:

Rabbit Polyclonal

Host: Rabbit Polyclonal

Conjugate:

Unconjugated

compare

(select up to 3 products from this page to compare)

MAB1128

BMP-2/BMP-4 Antibody (169125)

500 μg

Reactivity:

Ze

Species Glossary

Reactivity: Ze

Applications:

Applications:

Host:

Mouse Monoclonal

Host: Mouse Monoclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB1128U-100UG
Alexa Fluor 405	FAB1128V-100UG
Alexa Fluor 488	FAB1128G-100UG
Alexa Fluor 532	FAB1128X-100UG
Alexa Fluor 594	FAB1128T-100UG
Alexa Fluor 647	FAB1128R-100UG
Alexa Fluor 700	FAB1128N-100UG
Alexa Fluor 750	FAB1128S-100UG
Allophycocyanin	FAB1128A
Biotin	FAB1128B
CoraFluor 1	FAB1128CL1
DyLight 350	FAB1128D
DyLight 405	FAB1128E
DyLight 488	FAB1128K
DyLight 550	FAB1128L
DyLight 594	FAB1128M
DyLight 650	FAB1128W
DyLight 680	FAB1128Y
DyLight 755	FAB1128Z
FITC	FAB1128F
HRP	FAB1128H
Janelia Fluor 525	FAB1128JF525
Janelia Fluor 549	FAB1128I
Janelia Fluor 646	FAB1128J
Janelia Fluor 669	FAB1128JF669
PE	FAB1128P
PerCP	FAB1128C
mFluor Violet 450 SE	FAB1128MFV450
mFluor Violet 500 SE	FAB1128MFV500
mFluor Violet 610 SE	FAB1128MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	MAB1128-SP

compare

(select up to 3 products from this page to compare)

page of 1

Popular Products	Company Information	Support	Stay Connected
Antibodies Secondary Antibodies Isotype Controls Proteins and Peptides ELISA Kits Sample Size New Products	About Us Careers Novus Guarantee Contact Us Our Team	Technical Support FAQs Protocols

Visit our other sites

©2026 Novus Biologicals, All Rights Reserved.